Behavioral genetic study for early prediction of guide dog qualification

早期预测导盲犬资格的行为遗传学研究

• 批准号: 20880010
• 负责人: ARATA Sayaka
• 金额: $ 2.08万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (Start-up)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20880010/
• 关键词: 犬; 気質; アンケート評価; 生理学的反応; 神経伝達物質; 遺伝子多型; 一塩基置換; 盲導犬適性

With the aim of early predication of guide dog qualification, I examined temperament traits which had influence on guide dog qualification, and also searched for temperament-associated genes. A questionnaire survey on trainee dogs revealed that "Distraction" and "Docility" were consistently important for qualification. When these temperament scores and data from behavior tests (heart rates and behavioral responses) were employed for multivariate data analysis, guide dog qualification could be stably predicted with high accuracy (over 80%). Additionally, some genetic polymorphisms on neurotransmitter-related genes showed consistent association with "Distraction"and "Docility".

为了对导盲犬资质进行早期预测，本研究考察了影响导盲犬资质的气质性状，并寻找与导盲犬资质相关的基因。一项针对训练犬的问卷调查显示，“分心”和“温顺”一直是获得资格的重要条件。用这些气质得分和行为测试数据(心率和行为反应)进行多变量数据分析，可以稳定地预测导盲犬资格，准确率在80%以上。此外，神经递质相关基因上的一些遗传多态与“分心”和“驯服”表现出一致的关联。

项目成果

Temperament assessment on guide dogs using questionnaire survey and behaviour tests

通过问卷调查和行为测试对导盲犬进行气质评估

• 发表时间: 2009
• 作者: Arata;S.;Momozawa;Y.;Takeuchi;Y.;Mori;Y.
• 通讯作者: Y.

Sequences and Polymorphisms of the Canine Monoamine Transporter Genes SLC6A2, SLC6A3, and SLC6A4 among Five Dog Breeds

• DOI: 10.1292/jvms.70.971
• 发表时间: 2008-09-01
• 期刊: JOURNAL OF VETERINARY MEDICAL SCIENCE
• 影响因子: 1.2
• 作者: Arata, Sayaka;Ogata, Niwako;Mori, Yuji
• 通讯作者: Mori, Yuji

Important Behavioral Traits for Predicting Guide Dog Qualification

• DOI: 10.1292/jvms.09-0512
• 发表时间: 2010-05-01
• 期刊: JOURNAL OF VETERINARY MEDICAL SCIENCE
• 影响因子: 1.2
• 作者: Arata, Sayaka;Momozawa, Yukihide;Mori, Yuji
• 通讯作者: Mori, Yuji

Sequences of canine Glutamete Decarboxylase(GAD) l and GAD2 genes, and variation of their genetic polymorphisms among five dog breeds

犬谷氨酸脱羧酶(GAD)l和GAD2基因序列及5个犬种遗传多态性的变异

• 发表时间: 2008
• 期刊: Journal of Veterinary Medical Science 70
• 作者: Sayaka ARATA;Chie HASHIZUME;Takefumi KIKUSUI;Yukari TAKEUCHl and Yuji MORI
• 通讯作者: Yukari TAKEUCHl and Yuji MORI