Identifications for molecular mechanisms of essential hypertension in terms of urinary tubular ion transporter and human NEDD4L.
Identifications for molecular mechanisms of essential hypertension in terms of urinary tubular ion transporter and human NEDD4L.
批准号:
20590978
负责人:
ISHIGAMI Tomoaki
金额:
$3.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Nedd4L has been paid attention for its unique ubiquitinating properties that does an important working to cuticle sodium channel (ENaC) in the tubular epithelial cell and the post-transcriptional modification so far. Clarification and study results of the urinary tubular sodium re-absorption mechanism, and the role of Nedd4L in cardio-renal relationship is examined and the research announcement is done.
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Combining chronic kidney disease with 201thallium/123iodine beta methlyiodophenly pentadecanoic acid dual myocardial single-photon emission computed tomography findings is useful for the evaluation of cardiac event risk.
将慢性肾脏疾病与 201 铊/123 碘 β 甲基碘苯十五烷酸双心肌单光子发射计算机断层扫描结果相结合,可用于评估心脏事件风险。
DOI:
--
发表时间:
2009
期刊:
Nucl Med Commun 30
影响因子:
--
作者:
[Takamura, T, Ishigami, T, et al.]
通讯作者:
et al.
ALDOSTERONE INDEPENDENT ACTIVATION OF MINERALCORTIC OID RECEPTOR-SGK1 SYSTEMS IN URINARY EPITHELIUM FOR THE MODEL OF SODIUM SENSITIVE HYPERTENSION
醛固酮独立激活钠敏感性高血压模型尿上皮中盐皮质激素受体-SGK1系统
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ushio H, Ishigami T, et al.]
通讯作者:
et al.
DOI:
10.1152/ajprenal.00667.2009
发表时间:
2010-10-01
期刊:
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
影响因子:
4.2
作者:
[Masuda, Shin-ichiro, Tamura, Kouichi, Umemura, Satoshi]
通讯作者:
Umemura, Satoshi
Combining chronic kidney disease with201thallium/123iodine beta methyliodophenyl pentadecanoic acid dual myocardial single-photon emission computed tomography findings is useful for the evaluation of cardiac event risk.
将慢性肾病与 201 铊/123 碘 β 甲基碘苯基十五烷酸双心肌单光子发射计算机断层扫描结果相结合,可用于评估心脏事件风险。
DOI:
--
发表时间:
2009
期刊:
Nucl Med Commun. 30(1)
影响因子:
--
作者:
[Takamura T, Takahashi N, Ishigami T, Sugano T, Ishikawa T, Uchino K, Kimura K, Inoue T, Umemura S.]
通讯作者:
Umemura S.
ALDOSTERONE INDEPENDENT ACTIVATION OF MINERALCORTICOID RECEPTOR-SGK1 SYSTEMS IN URINARY EPITHELIUM FOR THE MODEL OF SODIUM SENSITIVE HYPERTENSION
钠敏感性高血压模型中醛固酮独立激活尿上皮盐皮质激素受体-SGK1系统
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ushio H, Ishigami T, et al.]
通讯作者:
et al.
共 24 条
Salt Sensitivity, Hypertension and Tubular Mechanism
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批准号:17K09730
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2017
-
负责人:ISHIGAMI Tomoaki
-
依托单位:
Elucidation and Expansion of Molecular Physiology of Salt Sensitivity and Hypertensin Based on Tubular Mechanism.
-
批准号:26461257
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
-
财政年份:2014
-
负责人:ISHIGAMI Tomoaki
-
依托单位:
Analyses of molecular mechanism of hypertensive cardio-renal relationships focusing on post-transcriptional regulations of ion-transporters.
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批准号:23591221
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2011
-
负责人:ISHIGAMI Tomoaki
-
依托单位:
Molecular Pathopbysiological Reseatch of ubiquitin ligase,human Nodd4L, for the development ofessentialhyportension
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批准号:18590898
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.49万
-
财政年份:2006
-
负责人:ISHIGAMI Tomoaki
-
依托单位:
海外基金