The neural basis of delusional misidentification in dementia with Lewy bodies

在路易体痴呆（DLB）中，妄想的患病率高于任何其他痴呆。对DLB患者各类妄想的主成分分析表明，误认妄想与妄想盗窃、妄想嫉妒等内容特异性妄想可能存在相互关系。此外，有皮质下缺血性血管病变的阿尔茨海默病患者妄想明显多于无缺血性血管病变的阿尔茨海默病患者。这一结果提示皮质下缺血性血管病变可能被认为是退行性痴呆患者妄想发生的危险因素。

In dementia with Lewy bodies (DLB) the prevalence of delusion was higher than that in any other dementia. The principal component analysis for all kinds of delusion in DLB revealed that misidentificational delusion and contents specific delusion such as delusional theft or delusional jealousy might related reciprocally.Furthermore, Alzheimer's disease patients with subcortical ischemic vascular lesionswere significantly more delusional than those without. This result suggests thatsubcortical ischemic vascular lesions may be considered as a risk factor for thedevelopment of delusions in degenerative dementia.