Effects of volatile anesthetic(Sevoflurane) on cardiac rhythm and ion channels
Effects of volatile anesthetic(Sevoflurane) on cardiac rhythm and ion channels
批准号:
20591796
负责人:
SUZUKI Akihiro
金额:
$2.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
We electro-physiologically studied the effect of sevoflurane, a volatile anesthesthetic widely used in Japan, on transient outward K (Ito) channel and slow delayed rectifier K (IKs) channel using the patch clamp technique. Sevoflurane suppressed the Ito in a concentration dependent manner. Sevoflurane also suppressed the IKs transfected on HEK cell. Our result indicated that the sevoflurane prolongs action potential by suppressing these potassium channel and may have a similar effect as class III anti-arrythmia drugs.
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影响因子:
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作者:
[]
通讯作者:
吸入麻酔薬が遅延整流Kチャネルに及ぼす影響の調査~タンパク発現マウスHEK細胞を用いて~
研究吸入麻醉剂对延迟整流 K 通道的影响 ~ 使用表达蛋白质的小鼠 HEK 细胞 ~
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Tsuchimochi K, Otero M, Dragomir CL, Plumb DA, Zerbini LF, Libermann TA, Marcu KB, Komiya S, Ijiri K, Goldring MB., 鈴木昭広]
通讯作者:
鈴木昭広
Regulation of root nodule formation by control of light quality and its application for legume production
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批准号:24658020
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2012
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负责人:SUZUKI Akihiro
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依托单位:
development of an economic experiment tool using mobile phone and examination of its effectiveness
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批准号:23530213
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2011
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负责人:SUZUKI Akihiro
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依托单位:
Analysis of molecular basis for enhanced symbiotic nitrogen fixation and its application for leguminous crops production.
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批准号:21380016
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.48万
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财政年份:2009
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负责人:SUZUKI Akihiro
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依托单位:
Root nodulation is controlled by sensing the R/ FR ratio through phytochrome signaling
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批准号:21657017
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.18万
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财政年份:2009
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负责人:SUZUKI Akihiro
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依托单位:
Preparation of nanosheet by CO_2 laser supersonic multi-drawing method and its application
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批准号:21350121
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.48万
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财政年份:2009
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负责人:SUZUKI Akihiro
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依托单位:
orthodontic tooth movement simulation based on the mechanical consideration of tissues
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批准号:21792056
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2009
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负责人:SUZUKI Akihiro
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依托单位:
Analysis of enhanced nitrogen fixation mutant of leguminous plant
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批准号:19580016
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2007
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负责人:SUZUKI Akihiro
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依托单位:
Studies on the structure and function of hemeproteins that use advantage of introduction of fluoroalkyl groups
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批准号:19550172
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:SUZUKI Akihiro
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依托单位:
Preparation of nanofiber and nanosheet by CO_2 laser nano-spinning method
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批准号:19350109
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$13.15万
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财政年份:2007
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负责人:SUZUKI Akihiro
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依托单位:
Research on reform in regional finance using simulation and experiment
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批准号:18530226
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.52万
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财政年份:2006
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负责人:SUZUKI Akihiro
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依托单位:
Preparation of nonwoven fabrics made from microfibers by using a carbon dioxide laser-thinning method
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批准号:17350105
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.86万
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财政年份:2005
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负责人:SUZUKI Akihiro
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依托单位:
Synthesis of heme substituted with fluoro and perfluoroalkyl groups, and application of fluorine nuclear to NMR-probe
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批准号:16550153
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.98万
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财政年份:2004
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负责人:SUZUKI Akihiro
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依托单位:
Preparation of microfibers by using a carbon dioxide laser and analysis of superstructure for obtained microfibers
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批准号:15350131
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.9万
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财政年份:2003
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负责人:SUZUKI Akihiro
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依托单位:
MCROSTRUCTURE AND MECHANICAL PROPERTIES OF POLYMERSOBTAINED BY LASER HEATING DRAWING METHOD
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批准号:12650880
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2000
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负责人:SUZUKI Akihiro
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依托单位:
CHANGES IN MICROSTRUCTURE OF POLYMERS HOT-DRAWN UNDER LOW FREQUENCY VIBRATION
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批准号:10650882
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:1998
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负责人:SUZUKI Akihiro
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依托单位:
海外基金