Cavernous nerve regeneration and recovery of erectile function following cavernous nerve injury

我们成功地通过单纯疱疹病毒载体介导的神经突触蛋白转导诱导了海绵体神经损伤后的海绵体神经再生。我们发现，单纯海绵体神经剥离可导致神经损伤相关的勃起功能障碍，炎症反应可能起作用。我们还发现，与年轻女性伴侣同居有助于功能恢复。在对人前列腺周围海绵体神经分布的研究中发现，勃起功能障碍患者的海绵体神经分布减少。

We successfully induced the cavernous nerve regeneration following cavernous nerve injury via herpes simplex virus vector-mediated delivery of neurturin. We found that cavernous nerve dissection alone caused nerve injury-related erectile dysfunction, and the inflammatory response could play the role. We also found that cohabitation with young female partner enhances the functional recovery. In the study of cavernous nerve distribution around the prostate in human, it is revealed that fiber distribution is decreased in the patients with erectile dysfunction.