Development of a novel therapeutic vaccine for precursor lesion of cervical cancer using mucosal immunity
Development of a novel therapeutic vaccine for precursor lesion of cervical cancer using mucosal immunity
批准号:
20591938
负责人:
KAWANA Kei
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Mucosal cellular immunity against HPV is necessary for clearance of precursor lesion of cervical cancer (CIN3) since CIN develops in the mucosal epithelium at cervix. This study demonstrated a strategy to induce mucosal anti-HPV cellular immune responses into the cervical mucosa and we started Phase I/IIa clinical trial of a novel therapeutic vaccine for treatment of CIN3 as a translational research.
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Human papillomavirus vaccines : current issues and future : Review.
人乳头瘤病毒疫苗:当前问题和未来:回顾。
DOI:
--
发表时间:
2009
期刊:
Indian J Med Res 130
影响因子:
--
作者:
[Kawana K, Yasugi T, Taketani Y]
通讯作者:
Taketani Y
HPVワクチンの導入とHPV関連癌の予防の可能性~子宮頸癌を中心に~
HPV疫苗的介绍以及预防HPV相关癌症的可能性 - 聚焦宫颈癌 -
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[鈴木嘉穂, 中林幸士, 武居智信, 松岡左希子, 陌間亮一, 竹村直也, 出口雅士, 森田宏紀, 吉田茂樹, 山田秀人, 川名敬]
通讯作者:
川名敬
DOI:
10.1111/j.1600-0897.2009.00715.x
发表时间:
2009-08-01
期刊:
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
影响因子:
3.6
作者:
[Iwasawa, Yuki, Fujii, Tomoyuki, Taketani, Yuji]
通讯作者:
Taketani, Yuji
A possible coagulation-independent mechanism for pregnancy 1 loss involving β2glycoprotein 1-dependent antiphospholipid antibodies and CD1d.
妊娠 1 丢失的一种可能的独立于凝血的机制涉及 β2 糖蛋白 1 依赖性抗磷脂抗体和 CD1d。
DOI:
--
发表时间:
2012
期刊:
Am J Reprod Immunol
影响因子:
3.6
作者:
[Iwasawa Y, Kawana K, Fujii T, Schust DJ, Nagamatsu T, Kawana Y, Sayama S, Miura S, Matsumoto J, Adachi K, Hyodo H, Yamashita T, Kozuma S, Taketani Y]
通讯作者:
Taketani Y
STRUCTURE-BASED STUDY OF VIRAL REPLICATION
基于结构的病毒复制研究
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Hiroshi Hand, Masaaki Kawano, R. Holland, Cheng]
通讯作者:
Cheng
共 28 条
Exploration of a new biomarker for companion diagnostics of HPV-targeting cancer immunotherapy
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批准号:18K09303
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2018
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负责人:KAWANA Kei
-
依托单位:
Basic research for development of immunotherapy for cervical cancer by using regenerative medicine (induced pluripotent stem cell: iPS cell)
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批准号:26293357
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.23万
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财政年份:2014
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负责人:KAWANA Kei
-
依托单位:
Studies on immunological strategy against gynecological cancers through mucosal immunity of reproductive tract mucosa.
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批准号:18591823
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.57万
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财政年份:2006
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负责人:KAWANA Kei
-
依托单位:
海外基金