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Gene Expression Profiling of Human Endolymphatic Sac by DNA Microarray Analysis

Gene Expression Profiling of Human Endolymphatic Sac by DNA Microarray Analysis
通过 DNA 微阵列分析人类内淋巴囊的基因表达谱
批准号:
20591982
负责人:
DOI Katsumi
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
To identify genesrelated to the pathogenesis of Meniere's disease (MD), gene expression profilings of the human endolymphatic sac (ES) harvested from the cases of both MD and Vestibular Schwannoma (VS) were determined by DNA microarray analysis. In the present study, we could successfully perform the DNA microarray analysis of the human ES. In spite of a tiny amount of total RNA obtained from this specialized tissue, approximately 7500 genes were identified to be there. In comparison of gene expression profiling between the human ES of both MD and VS cases, some genes were significantly up-regulated and others were down-regulated in the human ES of MD cases. The DNA microarray analysis in the present study may provide a large-scale understanding of gene expression profiling in the human ES and make it possible in future to identified the genes crossly related to the pathogenesis of MD.
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DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kitahara T., Doi K., Maekawa C, Kizawa K., Horii A., Kubo T., Kiyama H., 吉波和隆,北原糺,今井貴夫,大崎康宏,増村千佐子,木澤薫,岡崎鈴代,前川千絵,土井勝美,猪原秀典,堀井新, 北原糺,吉波和隆,川島貴之,今井貴夫,大崎康宏,木澤薫,増村千佐子,岡崎鈴代,前川千絵,土井勝美,猪原秀典,堀井新, 宮部淳二,宮口衛,堀井新,大崎康宏,北原糺,今井貴夫,土井勝美,猪原秀典, 前川千絵,北原糺,木澤薫,岡崎鈴代,増村千佐子,今井貴夫,土井勝美,猪原秀典,堀井新, 西村将彦,土井勝美,柿木章伸,竹田泰三]
通讯作者: 西村将彦,土井勝美,柿木章伸,竹田泰三
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DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kitahara T., Doi K., Maekawa C, Kizawa K., Horii A., Kubo T., Kiyama H., 吉波和隆,北原糺,今井貴夫,大崎康宏,増村千佐子,木澤薫,岡崎鈴代,前川千絵,土井勝美,猪原秀典,堀井新, 北原糺,吉波和隆,川島貴之,今井貴夫,大崎康宏,木澤薫,増村千佐子,岡崎鈴代,前川千絵,土井勝美,猪原秀典,堀井新, 宮部淳二,宮口衛,堀井新,大崎康宏,北原糺,今井貴夫,土井勝美,猪原秀典, 前川千絵,北原糺,木澤薫,岡崎鈴代,増村千佐子,今井貴夫,土井勝美,猪原秀典,堀井新, 西村将彦,土井勝美,柿木章伸,竹田泰三, 土井勝美]
通讯作者: 土井勝美
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DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kitahara T., Doi K., Maekawa C, Kizawa K., Horii A., Kubo T., Kiyama H., 吉波和隆,北原糺,今井貴夫,大崎康宏,増村千佐子,木澤薫,岡崎鈴代,前川千絵,土井勝美,猪原秀典,堀井新, 北原糺,吉波和隆,川島貴之,今井貴夫,大崎康宏,木澤薫,増村千佐子,岡崎鈴代,前川千絵,土井勝美,猪原秀典,堀井新, 宮部淳二,宮口衛,堀井新,大崎康宏,北原糺,今井貴夫,土井勝美,猪原秀典]
通讯作者: 宮部淳二,宮口衛,堀井新,大崎康宏,北原糺,今井貴夫,土井勝美,猪原秀典
DOI: 10.3109/00016480902897715
发表时间: 2010-01-01
期刊: ACTA OTO-LARYNGOLOGICA
影响因子: 1.4
作者: [Hikita-Watanabe, Noriko, Kitahara, Tadashi, Okumura, Shin-Ichi]
通讯作者: Okumura, Shin-Ichi
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