Mechanisms of taste cell differentiation : interaction between taste cells and taste nerves in reconstruction system
Mechanisms of taste cell differentiation : interaction between taste cells and taste nerves in reconstruction system
批准号:
20592177
负责人:
HARADA Shuitsu
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
分析了味觉神经参与了味觉细胞分化的区域性差异,以及软腭部和菌状乳头味觉转导机制的区域性差异。我们的结果表明,味觉神经可能不参与味觉细胞分化的区域差异,苦味转导的差异可能不仅是由于G-α蛋白的差异,也是由于苦味受体的差异。
英文摘要
The involvement of taste nerves in the regional differences in taste cell differentiation, and the regional differences in taste transduction machinery were analyzed between the soft palate and fungiform papillae. Our results suggested that taste nerves may not be involved in the regional differences in taste cell differentiation, and that the difference in bitter taste transduction may be caused by the differences in not only Gα proteins but also bitter taste receptors.
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Lrmp/Jawl is expressed in sweet, bitter and umami receptor-expressing cells.
Lrmp/Jawl 在甜味、苦味和鲜味受体表达细胞中表达。
DOI:
--
发表时间:
2010
期刊:
Chem Senses
影响因子:
3.5
作者:
[Shindo Y, Kim MR, Miura H, Yuuki T, Kanda T, Hino A, Kusakabe Y]
通讯作者:
Kusakabe Y
DOI:
10.1016/j.bbrc.2008.09.035
发表时间:
2008-11-21
期刊:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子:
3.1
作者:
[Shindo, Yoichiro, Miura, Hirohito, Kusakabe, Yuko]
通讯作者:
Kusakabe, Yuko
Galphal4 is a candidate mediator of sweet/umami signal transduction in the posterior region of the mouse tongue.
Galpha14是小鼠舌头后部区域甜味/鲜味信号转导的候选介质。
DOI:
--
发表时间:
2008
期刊:
Biochem Biophys Res Commun. 376
影响因子:
--
作者:
[Shindo Y, Miura H, Carninci P, Kawai J, Hayashizaki Y, Ninomiya Y, Hino A, Kanda T, Kusakabe Y]
通讯作者:
Kusakabe Y
味蕾細胞特異的に発現する遺伝子の口腔内の部位による多様な発現様式
味蕾细胞中特异性表达的基因的不同表达模式取决于口腔中的部位
DOI:
--
发表时间:
2009
期刊:
味と匂学会誌 Vol.16, No.3
影响因子:
--
作者:
[日下部裕子, 進藤洋一郎, 三浦裕仁, カルニンチ ピエロ, 河合純, 林崎良英, 二ノ宮裕三, 日野明寛]
通讯作者:
日野明寛
Cell differentiation of the taste buds on the soft palate and fungiform papillae reconnected to different gustatory nerves
软腭上味蕾的细胞分化和与不同味觉神经重新连接的菌状乳头
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[原田秀逸, 友成博, 中山歩, 進藤洋一郎, 日下部裕子, 三浦裕仁]
通讯作者:
三浦裕仁
共 30 条
Functions and species differences of softpalate taste buds in mammals
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批准号:18592041
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.27万
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财政年份:2006
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负责人:HARADA Shuitsu
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依托单位:
Synergistic taste effectiveness of citric acid
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批准号:10470358
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$4.35万
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财政年份:1998
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负责人:HARADA Shuitsu
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依托单位:
Developmental alteration of function and distribution of taste buds on the soft palate.
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批准号:06671865
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1994
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负责人:HARADA Shuitsu
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依托单位:
Morphological and functional changes of taste buds on the soft palate during development.
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批准号:04671126
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1992
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负责人:HARADA Shuitsu
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依托单位:
Coding of gustatory information in the NTS from the soft palate.
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批准号:02807170
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.96万
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财政年份:1990
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负责人:HARADA Shuitsu
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依托单位:
海外基金