Cortico-cortical connection involved in complex regulation of mastication

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The aim of this study was to clarify the role of cortico-cortical connection from the cortical masticatory area, to which repetitive electrical stimulation evoked the rhythmical jaw movements, on control of masticatory movements. In guinea pigs, the area inducing the rhythmical chewing-like movements (C-area) located posterolateral to the face primary motor cortex (face-MI). The cotico-cortical connection from the C-area to the face-MI was found electrophysiologically and histologically Furthermore, it was found that this connection played an important role on evoking the rhythmical jaw movement by stimulation to the C-area