Influence of occlusal interferance and masticatory disturbance on antioxidant capacity in serum

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Occlusion and mastication are indispensable factors in maintaining health, and when these functions are not normally practiced, stress is put on the body, causing various affects. Meanwhile, it has been verified that free radicals such as superoxide increase due mental/physical stress, thus evoking various diseases. Therefore, in this study, we investigated both the occurrence of a mastication disturbance which requires changing the breeding feed of rats from solid to liquids, and also the presence of occlusal interference due to the premature contact. As a result, the superoxide production ability of neutrophil was enhanced while the serum superoxide dismutase (SOD) activity declined. That is to say, the feeding of liquid feed and occlusal interference became stressors to rats that normally chew, and this was proven to induce oxidative stress in the body.