Development of implant surface modification method for rapid osteoconductivity and gingival epithelial adhesiveness

采用小鼠源性牙龈上皮细胞（GE1）检测种植体牙龈穿透部位上皮细胞的粘附性，观察细胞的初始附着和细胞增殖情况。对于在氯化钙溶液中进行水热处理的钛，GE1细胞的初始附着率明显高于未处理的钛。在细胞增殖方面，虽然未处理的钛有一些高值，但没有明显差异。因此，我们认为CaCl2水热处理可以改善钛种植体牙龈穿透部分的牙龈粘连性。

Initial cell attachment and cell proliferation were examined by using gingival epithelial cell (GE1) of mouse origin to examine adhesiveness of epithelial cell of implant in gingival penetration part. As for the titanium treated by hydrothermally in calcium chloride solution, the result of initial attachment of GE1 cell was significantly high compared with untreated titanium. As for the cell proliferation, a significant difference was not admitted though the untreated titanium indicated some high values. Therefore, it was suggested that the hydrothermal treatment with CaCl2 was able to improve the gingiva adhesiveness in the gingiva penetration part of the titanium implant.