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Pain sensations of oral region in rat models of Parkinson's disease

Pain sensations of oral region in rat models of Parkinson's disease
帕金森病模型大鼠口腔疼痛感觉
批准号：
20592371
负责人：
NIWA Hitoshi
金额：
$2.91万
依托单位：
Osaka University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2008
资助国家：
日本
项目状态：
已结题
起止时间：
2008 至 2010
来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592371/
关键词：
パーキンソン病痛覚三叉神経疼痛関連行動c-Fosホルマリンテスト痔痛関連行動疼痛感覚ホルマチンテスト体性感覚誘発電位ラット

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中文摘要
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英文摘要
Parkinson's disease model rats (PD rat) were injected formalin into the left upper lip. The numbers of pain-related-behavior (PRB) and c-Fos or ERK positive cells in the trigeminal nucleus caudalis were counted after formalin injection. PD rats with contralateral injection showed a decrease in PRB during the first 5 min, however, there was no significant change in ERK expression compared with sham rats. The number of PRBs and c-Fos expression increase in PD rats with ipsilateral injection. These results suggest that the PD rat is in hyperalgesia, however, the behavioral response to pain is blunted.
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Behavioral responses and Fos expression following facial painful stimuli in hemi-parkinsonian rats
偏侧帕金森病大鼠面部疼痛刺激后的行为反应和 Fos 表达
DOI： --
发表时间： 2010
期刊：
影响因子： --
作者： [Maegawa H, Sugiyo A, Masawaki A, Oyamaguti A, Yoshida A, Kato T, Niwa H]
通讯作者： Niwa H
Behavioral responses and Fos activation following orofacial formalin injection in a rodent model of Parkinson's disease
  • 批准号：
    23592988
  • 项目类别：
    Grant-in-Aid for Scientific Research (C)
  • 资助金额：
    $3.33万
  • 财政年份：
    2011
  • 负责人：
    NIWA Hitoshi
  • 依托单位：
    Osaka University
The effects of acupuncture on endocrine system, autonomic nervous system and cerebral function
  • 批准号：
    17592076
  • 项目类别：
    Grant-in-Aid for Scientific Research (C)
  • 资助金额：
    $2.18万
  • 财政年份：
    2005
  • 负责人：
    NIWA Hitoshi
  • 依托单位：
    Osaka University
How are the cells on the surface of embryoid body derived from ES cells induced to differentiate into primitive endoderm?
  • 批准号：
    16370099
  • 项目类别：
    Grant-in-Aid for Scientific Research (B)
  • 资助金额：
    $9.34万
  • 财政年份：
    2004
  • 负责人：
    NIWA Hitoshi
  • 依托单位：
    RIKEN
ESTABLISHMENT OF FEEDER- AND SERUM-FREE CULTURE SYSTEM OF ES CELLS AND ITS APPLICATION TO PROPAGATE ES CELLS FROM INBRED MICE EMBRYOS
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