Neural mechanism of episodic memory

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We trained a monkey to perform an episodic memory task. In three display panels, we created a virtual maze. The monkey was required to find a target object in the maze through exploring the environment with operating a joystick. The monkey learned the task and could reach the target object faster in the following trial than the exploring trial. In addition, we trained rats to perform an episodic memory task using 8-arms radial maze. In the task, the rats had to remember what-where-when information. We next examine the neural mechanisms of the episodic memory through lesion studies and studies with recording the neuronal activity.