Influence of physical agents on peripheral nerve regeneration and skin lesion after transection of the mouse sciatic nerve.

物理因素对小鼠坐骨神经横断后周围神经再生和皮肤病变的影响。

• 批准号: 20700449
• 负责人: OGATA Akiko
• 金额: $ 2.33万
• 依托单位: Kobe Gakuin University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20700449/
• 关键词: リハビリテーション; 物理療法; 末梢神経損傷

To preserve property of the muscle and skin from degeneration is one of the most important things until peripheral nerve regeneration was completed. In this study, to evaluate the effective of physical agents on peripheral nerve regeneration, we investigate that physical agents, such as electrical stimulation, ultrasound, promoted the environment to be suitable for mature of regenerating nerve fiber.This study demonstrates that the development of mouse model of pressure ulcer by intensive mechanical loads, and this model was adequate to study the effects of physical agents on wound healing. In addition, we were able to show that ultra sound might be useful tools to accelerate morphological and functional reconstruction on skin lesion and regenerating nerve

在周围神经再生完成之前，保护肌肉和皮肤的性质不受变性的影响是最重要的事情之一。本研究通过电刺激、超声波等物理刺激手段促进周围神经纤维再生，建立了小鼠压力性溃疡模型，并通过实验验证了该模型的可行性，为进一步研究物理刺激对创伤愈合的影响提供了实验依据。此外，我们能够表明，超声可能是有用的工具，以加速形态和功能重建的皮肤病变和再生神经