Functional Strontium Phosphate Coated Magnesium Alloys For ?Orthopaedic Use

骨科用功能性磷酸锶涂层镁合金

• 批准号: LP150100343
• 负责人: A/Prof Xiao-Bo Chen
• 金额: $ 19.82万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-02-26 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP150100343
• 关键词: Functional; Strontium; Phosphate; Coated; Magnesium

This project aims to develop a functional strontium-release surface on magnesium-based orthopaedic implants to suppress the rapid degradation rate of magnesium, facilitate new bone formation and ultimately shorten the healing process. The development of practical, bone-favourable and degradation-inhibiting surfaces for magnesium implants are in demand and can bring significant patient benefits. The project seeks to establish an understanding of the formation mechanisms of strontium-releasing coatings and determine the critical release rate of strontium to activate bone cell responses.

该项目旨在开发镁基骨科植入物上的功能性锶释放表面，以抑制镁的快速降解速率，促进新骨形成并最终缩短愈合过程。镁植入物的实用，骨有利和抑制降解的表面的发展是有需求的，可以带来显着的患者利益。该项目旨在了解锶释放涂层的形成机制，并确定激活骨细胞反应的锶临界释放速率。