Nested case-control study to clarify a preventive factor of lung cancer.

1)我们在一项前瞻性队列研究中调查了维生素E摄入量与肺癌风险之间的关系。异黄酮摄入量可能与肺癌风险降低有关，仅在从不吸烟者中。2)我们对队列中的女性进行了巢式病例对照研究，发现血浆染料木黄酮水平与肺癌风险呈负相关。通过不同方法评估的肺癌风险降低的相关性支持了肺癌预防因素的可能性。

1) We investigated the association between isoflavone intake and lung cancer risk in a prospective cohort study. Isoflavone intake may be associated with a decreased risk of lung cancer in never smokers only. 2) We conducted a nested case-control study among women within the cohort, and found an inverse association between plasma level of genistein and lung cancer risk. The associations of isoflavone assessed by different methods with a decreased risk of lung cancer support the possibility that isoflavone is a preventive factor of lung cancer.