Formation and Osteoconductivity of Anodized TiO2 Coating with Functional Group

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Titania-coated titanium implants were formed using anodizing processing in various kinds of solutions. These TiO2 fims had anion, cation and/or functional groups, which were existed in the aqueous solutions used in anodizing. Titanium rods with TiO2 coating were implanted in rats tibia for 14 days, and osteoconductivity was evaluated from the amount of hard tissue formed on the implants. As a result, it was clear that anion, cation and/or functional groups in the films did not influence on the osteoconductivity. However, their osteoconductivity was strongly depended on the hydrophilicity/hydrophobicity of TiO2 surface. That is to say that the hydrophilicity surface had high osteoconductivity.