Synthesis of macrocyclic compounds that change their conformation depending on the external environment of stimulus

在这个项目中，我们合成了可以根据外界环境或刺激改变空腔大小的大环化合物。含有酰胺键的大环化合物通过化学引入或去掉酰胺氮上的烷基来改变其构象。此外，含有偶氮键的大环化合物通过紫外光照射或加热改变了其构象。

In this project, large macrocyclic compounds that could change the size of the cavity depending on the external environment or stimulus were synthesized. The macrocyclic compound which contains the amide linkages changed its conformation by chemical introduction or removal of alkyl groups on the amide nitrogens. Furthermore, the macrocyclic compound which contains the azo linkages changed its conformation by irradiating of UV light or heating.