Physiological significance of tight junction cation selectivity for Na-dependent sugar absorption in the small intestine
Physiological significance of tight junction cation selectivity for Na-dependent sugar absorption in the small intestine
批准号:
21590236
负责人:
SUZUKI Yuichi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
Glucose and many other nutrients absorption in the mammalian small intestine are mediated by Na-dependent active transport mechanism. The present results have suggested that Na required for these processes is rapidly supplied from the blood side to the lumen through the tight junction, and claudin-15 play a major role in this pathway.
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DOI:
10.1053/j.gastro.2010.08.006
发表时间:
2011-03-01
期刊:
GASTROENTEROLOGY
影响因子:
29.4
作者:
[Tamura, Atsushi, Hayashi, Hisayoshi, Tsukita, Sachiko]
通讯作者:
Tsukita, Sachiko
腸管上皮タイト結合部の陽イオン選択透過性のNa+依存性栄養素吸収における役割
肠上皮紧密连接的阳离子选择性通透性在Na+依赖性营养吸收中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[鈴木裕一, 林久由]
通讯作者:
林久由
Na依存性グルコース吸収におけるタイト結合部のNa透過性の役割
紧密连接钠渗透性在钠依赖性葡萄糖吸收中的作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[林久由, 他]
通讯作者:
他
Na+-依存性グルコース吸収におけるタイト結合部のNa+透過性の役割
紧密连接 Na+ 通透性在 Na+ 依赖性葡萄糖吸收中的作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[林久由, 鈴木裕一, 田村淳, 月田早智子]
通讯作者:
月田早智子
Proteinase-activated receptors-1 and 2 induce electrogenic Cl-secretion in the mouse cecum by distinct mechanisms
蛋白酶激活受体 1 和 2 通过不同的机制诱导小鼠盲肠中的电 Cl 分泌
DOI:
--
发表时间:
2010
期刊:
Am. J. Physiol
影响因子:
--
作者:
[Ikehara O, Hayashi H, Watanabe Y, Yamamoto H, Mochizuki T, Hoshino M, Suzuki Y.]
通讯作者:
Suzuki Y.
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Spatial variation of hydraulic conductivity and its effects on groundwater flow
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