Molecular epidemiological study on the evaluation of long-term intake of folic acid, in order to reduce the risk of Down syndrome

评估长期摄入叶酸以降低唐氏综合症风险的分子流行病学研究

• 批准号: 21590699
• 负责人: TAKAMURA Noboru
• 金额: $ 2.91万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21590699/
• 关键词: 母子保健; ダウン症候群; 葉酸

We showed that genetic effects of MTHFR polymorphism on homosysteine metabolism is different in three generations, i. e. new born babies, mothers and elderies.

结果表明，MTHFR基因多态性对同型半胱氨酸代谢的遗传效应在三个世代中是不同的。e.新生儿、母亲和老人。

项目成果

Body mass index positively correlated with forced expiratory volume in 1 second / forced vital capacity in population with relatively low prevalence of obesity.

在肥胖患病率相对较低的人群中，体重指数与 1 秒用力呼气量/用力肺活量呈正相关。

• 发表时间: 2010
• 期刊: Chin Med J
• 作者: Fukahori S;他
• 通讯作者: 他

Leptin is an independent determinant of bone mineral density in men with type 2 diabetes mellitus

瘦素是 2 型糖尿病男性骨矿物质密度的独立决定因素

• 发表时间: 2011
• 期刊: Acta Diabetol
• 影响因子: 3.8
• 作者: Vasilkova O;Mikhort T;Sanec I;Sharshakova T;Hayashida N;Takamura N
• 通讯作者: Takamura N

White blood cell count and cardiovascular biomarkers of atherosclerosis.

白细胞计数和动脉粥样硬化的心血管生物标志物。

• 发表时间: 2010
• 期刊: Biomarkers
• 影响因子: 2.6
• 作者: Sekitani Y;Hayashida N;Kadota K;Yamasaki H;Abiru N;Nakazato M;Maeda T;Ozono Y;Takamura N
• 通讯作者: Takamura N

Evaluation of 137Cs body burden in inhabitants of Bryansk Oblast, Russian Federation, where a high incidence of thyroid cancer was observed after the accident at the Chernobyl nuclear power plant

• DOI: 10.1093/rpd/ncq137
• 发表时间: 2010-09-01
• 期刊: RADIATION PROTECTION DOSIMETRY
• 影响因子: 1
• 作者: Sekitani, Yui;Hayashida, Naomi;Takamura, Noboru
• 通讯作者: Takamura, Noboru

A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasma.

• DOI: 10.1002/bmc.1205
• 发表时间: 2009-09
• 期刊: Biomedical chromatography : BMC
• 作者: S. Ichinose;Mayumi Nakamura;Mayu Maeda;Rie Ikeda;M. Wada;M. Nakazato;Y. Ohba;N. Takamura;T. Maeda;K. Aoyagi;K. Nakashima