Investigation of the risk factors for triple negative breast cancer

三阴性乳腺癌危险因素调查

• 批准号: 21590726
• 负责人: NISHINO Yoshikazu
• 金额: $ 2.66万
• 依托单位: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所) (2011)Miyagi Cancer Center Research Institute (2009-2010)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21590726/
• 关键词: 癌; 疫学; 危険因子; 乳癌; トリプルネガティブ

The risk for triple negative breast cancer in relation to lifestyle factors was investigated by case-control study including 107 triple negative breast cancer cases and 1659 hospital controls who were diagnosed and admitted in Miyagi Cancer Center between 2002 and 2009. Family history of breast cancer was associated with increased risk for triple negative breast cancer, and late age at menarche was related to decreased risk of it. Furthermore, reduced risk associated with increasing intake of green tea, Chinese tea, carrot and pumpkin, and tomato was observed. This study provides important findings on prevention of triple negative breast cancer.

通过病例对照研究调查了与生活方式因素相关的三阴性乳腺癌风险，包括2002年至2009年期间在宫城癌症中心诊断并住院的107例三阴性乳腺癌病例和1659例医院对照。乳腺癌家族史与三阴性乳腺癌风险增加相关，月经初潮年龄晚与三阴性乳腺癌风险降低相关，此外，观察到增加绿色茶、中国茶、胡萝卜和南瓜以及番茄的摄入量与三阴性乳腺癌风险降低相关。这项研究为预防三阴性乳腺癌提供了重要的发现。

项目成果

Effect of screening mammography on breast cancer survival in comparison to other detection methods: A retrospective cohort study

• DOI: 10.1111/j.1349-7006.2009.01212.x
• 发表时间: 2009-08-01
• 期刊: CANCER SCIENCE
• 影响因子: 5.7
• 作者: Kawai, Masaaki;Kuriyama, Shinichi;Ohuchi, Noriaki
• 通讯作者: Ohuchi, Noriaki

Being breastfed in infancy and adult breast cancer risk among Japanese women

• DOI: 10.1007/s10552-011-9888-3
• 发表时间: 2012-02-01
• 期刊: CANCER CAUSES & CONTROL
• 影响因子: 2.3
• 作者: Minami, Yuko;Nishino, Yoshikazu;Kakugawa, Yoichiro
• 通讯作者: Kakugawa, Yoichiro