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Therapeutic approaches targeting colonic myofibroblasts-derived IL-24 in inflammatory bowel disease.

Therapeutic approaches targeting colonic myofibroblasts-derived IL-24 in inflammatory bowel disease.
针对炎症性肠病中结肠肌成纤维细胞衍生的 IL-24 的治疗方法。
批准号:
21590809
负责人:
ANDO Akira
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
we demonstrated that IL-24 expression is enhanced in the inflamed mucosa of active IBD patients. Colonic SEMFs-derived IL-24 appears to play a protective role in the pathophysiology of IBD via a stimulation of STAT3 activation in cells mediating the innate immune response.
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DOI: 10.4049/jimmunol.0804169
发表时间: 2009-07-01
期刊: JOURNAL OF IMMUNOLOGY
影响因子: 4.4
作者: [Andoh, Akira, Shioya, Makoto, Fujiyama, Yoshihide]
通讯作者: Fujiyama, Yoshihide
DOI: 10.1007/s00535-011-0474-y
发表时间: 2012-02-01
期刊: JOURNAL OF GASTROENTEROLOGY
影响因子: 6.3
作者: [Imaeda, Hirotsugu, Andoh, Akira, Fujiyama, Yoshihide]
通讯作者: Fujiyama, Yoshihide
Accuracy of genotyping using the TaqMan PCR assay for single nucleotide polymorphisms responsible for thiopurine sensitivity in Japanese patients with inflammatory bowel disease
使用 TaqMan PCR 检测对日本炎症性肠病患者硫嘌呤敏感性的单核苷酸多态性进行基因分型的准确性
DOI: --
发表时间: 2011
期刊: Exp Ther Med
影响因子: 2.7
作者: [Osaki R, Imaeda H, Ban H, Aomatsu T, Bamba S, Tsujikawa T, Sasaki M, Fujiyama Y, Andoh A]
通讯作者: Andoh A
DOI: 10.3892/ijmm.2011.718
发表时间: 2011-10-01
期刊: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
影响因子: 5.4
作者: [Imaeda, Hirotsugu, Andoh, Akira, Fujiyama, Yoshihide]
通讯作者: Fujiyama, Yoshihide
6
    Development of a high-intensity optical cavity and a photo-neutralizer for high energy negative ion beams
    • 批准号:
      18H01197
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.98万
    • 财政年份:
      2018
    • 负责人:
      ANDO Akira
    • 依托单位:
    New concept of electric propulsion using a liquid metal sputtering
    • 批准号:
      18K18907
    • 项目类别:
      Grant-in-Aid for Challenging Research (Exploratory)
    • 资助金额:
      $3.99万
    • 财政年份:
      2018
    • 负责人:
      ANDO Akira
    • 依托单位:
    Study on Work-Life Design focusing on Quality of Work
    • 批准号:
      16K12669
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.25万
    • 财政年份:
      2016
    • 负责人:
      ANDO Akira
    • 依托单位:
    Development of the new type ion engine using a reflected-type negative ion source
    • 批准号:
      24654187
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2012
    • 负责人:
      ANDO Akira
    • 依托单位:
    海外基金