课题基金 / 基金详情

Mechanism of drug resistance by Epithelial-Mesenchymal Transition and bone marrow stem cell

Mechanism of drug resistance by Epithelial-Mesenchymal Transition and bone marrow stem cell
上皮间质转化和骨髓干细胞的耐药机制
批准号:
21591720
负责人:
TSUTSUMI Soichi
金额:
$0.42万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

项目摘要

项目成果

TSUTSUMI Soichi的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The epithelial to mesenchymal transition(EMT)is a molecular process through which an epithelial cell undergoes differentiation into a mesenchymal phenotype. The relationship between EMT and resistance to an anti-cancer drug in colorectal cancer remains unknown. In this study, we investigated the acquisition of EMT by 5-FU in colorectal cell lines. 5-FU resistant cell lines did not change into a mesenchymal phenotype. This study suggests that EMT phenotype may not play a significant role in anti-cancer agent resistance in colorectal cancer
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI: --
发表时间: 2010
期刊: Int J Colorectal Dis
影响因子: 2.8
作者: [Tabe Y, Mochiki E, Yanai M, Toyomasu Y, Ando H, Ohno T, Tsutsumi S, Asao T, Kuwano H]
通讯作者: Kuwano H
Phosphoglucose isomerase enhances colorectal cancer metastasis
磷酸葡萄糖异构酶增强结直肠癌转移
DOI: --
发表时间: 2009
期刊: Int J Oncol 35
影响因子: --
作者: [Sato M, Shibata C, Kikuchi D, Ikezawa F, Imoto H, Kakyo M, Kinouchi M, Tanaka N, Miura K, Naitoh T, Ogawa H, Sasaki I, 島田英昭, Soichi Tsutsumi]
通讯作者: Soichi Tsutsumi
DOI: 10.1016/j.ejca.2010.02.021
发表时间: 2010-07-01
期刊: EUROPEAN JOURNAL OF CANCER
影响因子: 8.4
作者: [Li, Jie, Hou, Ni, Kuwano, Hiroyuki]
通讯作者: Kuwano, Hiroyuki
DOI: 10.1186/1471-2407-11-216
发表时间: 2011-06-02
期刊: BMC cancer
影响因子: 3.8
作者: [Fujii T, Tabe Y, Yajima R, Yamaguchi S, Tsutsumi S, Asao T, Kuwano H]
通讯作者: Kuwano H
20
    Immunotherapy of carcinomatous pleuritis and peritonitis targeting phosphoglucose isomerase as a vaccine.
    • 批准号:
      16591246
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.46万
    • 财政年份:
      2004
    • 负责人:
      TSUTSUMI Soichi
    • 依托单位:
    海外基金