The study for solution of rupture and glowing of cerebral aneurysms using the novel flow simulation methods with MRI

背景：颅内动脉瘤的血流动力学被认为在其生长和破裂中起重要作用。基于三维（3D）计算机断层摄影（CT）血管造影术的血管计算机流体动力学（CFD）需要耗时的分析过程。基于磁共振图像的磁共振流体动力学（MRFD）是分析流体动力学的一种新工具，也是一种很有前途的方法，可以更容易地获得这些信息。方法：对15例患者共15个动脉瘤（包括2个破裂动脉瘤）进行MR成像和3D-CT血管造影检查。结果：MRFD和CFD的三维流场、三维流线、流速分布和壁面切应力（WSS）图基本一致，MRFD和CFD的三维流场、流速分布和壁面切应力图基本一致。然而，最大WSS的计算值相差很大，没有显著相关性。此外，在一个破裂的情况下，CFD显示较少的可视化，以评估颅内血流。

BACKGROUND : Hemodynamics in intracranial aneurysms is thought to play an important role in their growth and rupture. Usual computed fluid dynamics(CFD) based on three-dimensional(3D) computed tomographic(CT) angiography requires a time-consuming process for analysis. Magnetic resonance fluid dynamics(MRFD) based on MR images is a new tool for analyzing flow dynamics and a promising method for obtaining such information more easily. We compared the data from MRFD and CFD and studied the clinical feasibility of MRFD.METHODS : A total of15aneurysms, including two ruptured ones, in15patients were investigated with MR imaging and 3D-CT angiography. The flow data of MRFD and CFD, 3D stream lines, flow velocity profile and wall shear stress(WSS) were extracted from the image reconstruction and were compared each other.RESULTS : Both flow dynamics images showed quite similar 3D flow pattern and WSS map. However, the calculated value of maximum WSS was quite different and there was no significant correlation. Further, in one ruptured case, CFD showed less visualization to evaluate the intra-aneurysmal flow.