Identification of molecules associated with intravesical recurrence of non-muscle invasive bladder cancer and the development of novel therapeutic strategy based on the molecular mechanism
Identification of molecules associated with intravesical recurrence of non-muscle invasive bladder cancer and the development of novel therapeutic strategy based on the molecular mechanism
批准号:
21592045
负责人:
MIYAKE Hideaki
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
Through the evaluation of molecules associated with cell cycle, cell adherence and EMT, we developed predictive systems for intravesical recurrence of non-muscle invasive bladder cancer. In addition, we suggested the usefulness of novel therapeutic strategy targeting these molecules for preventing intravesical recurrence of non-muscle invasive bladder cancer.
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Growth inhibition and chemosensitization in human bladder cancer KoTCC-1 cells by siRNA targeting heat shock protein-70
靶向热休克蛋白70的siRNA对人膀胱癌KoTCC-1细胞的生长抑制和化疗增敏
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Hideaki Miyake, Tomoaki Terakawa, Iori Sakai, Junya Furukawa, Yuji Kusuda, Mototsugu Muramaki, Atsushi Takenaka, Masato Fujisawa]
通讯作者:
Masato Fujisawa
Expression of cell cycle-associated proteins in superficial bladder cancer : correlation with intravesical recurrence following transurethral resection
浅表性膀胱癌中细胞周期相关蛋白的表达:与经尿道切除术后膀胱内复发的相关性
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Miyake H, 他5名(2番目)]
通讯作者:
他5名(2番目)
DOI:
10.1016/j.urolonc.2010.01.005
发表时间:
2012-03-01
期刊:
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
影响因子:
2.7
作者:
[Muramaki, Mototsugu, Miyake, Hideaki, Fujisawa, Masato]
通讯作者:
Fujisawa, Masato
Expression of integrin proteins in non-muscle invasive bladder cancer : significance of intravesical recurrence following transurethral resection
整合素蛋白在非肌层浸润性膀胱癌中的表达:经尿道切除术后膀胱内复发的意义
DOI:
--
发表时间:
2010
期刊:
BJU International
影响因子:
4.5
作者:
[Miyake H, (他5名, 2番目)]
通讯作者:
2番目)
Investigation of the molecular mechanism mediating the acquired resistance to docetaxel in castration-resistant prostate cancer and the development of the novel therapy targeting this mechanism
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批准号:18K09164
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2018
-
负责人:MIYAKE Hideaki
-
依托单位:
Investigation of mechanism mediating resistant phenotype of renal cell carcinoma to tyrosine kinase inhibitors and development of novel therapy to ovetrcome its resistance
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批准号:24592389
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:MIYAKE Hideaki
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依托单位:
Development of novel therapies based on the progression mechanism in prostate cancer involving the seminal vesicle
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批准号:19591848
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:MIYAKE Hideaki
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依托单位:
海外基金