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Development of novel therapies based on the progression mechanism in prostate cancer involving the seminal vesicle

Development of novel therapies based on the progression mechanism in prostate cancer involving the seminal vesicle
基于累及精囊的前列腺癌进展机制开发新疗法
批准号:
19591848
负责人:
MIYAKE Hideaki
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008

项目摘要

项目成果

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中文摘要
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英文摘要
精嚢抽出液の添加により前立腺癌細胞の浸潤能の顕著な亢進が認められ,この現象が精嚢抽出液中のTGFβによるuPAの発現誘導によるものであることを証明した.また,前立腺癌におけるuPA/uPA receptor systemが,根治的前立腺全摘除術施行後の予後に重要な役割を果たすことを明らかにした.
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会议论文
DOI: 10.1016/j.urolonc.2008.08.001
发表时间: 2010-03-01
期刊: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
影响因子: 2.7
作者: [Miyake, Hideaki, Muramaki, Mototsugu, Fujisawa, Masato]
通讯作者: Fujisawa, Masato
DOI: 10.1038/sj.bjc.6604169
发表时间: 2008-01-22
期刊: BRITISH JOURNAL OF CANCER
影响因子: 8.8
作者: [Kumano, M., Miyake, H., Fujisawa, M.]
通讯作者: Fujisawa, M.
DOI: 10.1016/j.urolonc.2008.01.012
发表时间: 2009-03-01
期刊: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
影响因子: 2.7
作者: [Kumano, Masafumi, Miyake, Hideaki, Fujisawa, Masato]
通讯作者: Fujisawa, Masato
Expression of potential molecular markers in prostate cancer : correlation with clinicnpatliological outcomes in patients undergoing radical prostatectomy
前列腺癌中潜在分子标志物的表达:与接受根治性前列腺切除术的患者临床病理结果的相关性
DOI: --
发表时间:
期刊: Urol Oncol (掲載確定) in press
影响因子: --
作者: [Miyake H, 他5名, 1番目]
通讯作者: 1番目
8
    Investigation of the molecular mechanism mediating the acquired resistance to docetaxel in castration-resistant prostate cancer and the development of the novel therapy targeting this mechanism
    • 批准号:
      18K09164
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.75万
    • 财政年份:
      2018
    • 负责人:
      MIYAKE Hideaki
    • 依托单位:
    Investigation of mechanism mediating resistant phenotype of renal cell carcinoma to tyrosine kinase inhibitors and development of novel therapy to ovetrcome its resistance
    • 批准号:
      24592389
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.41万
    • 财政年份:
      2012
    • 负责人:
      MIYAKE Hideaki
    • 依托单位:
    Identification of molecules associated with intravesical recurrence of non-muscle invasive bladder cancer and the development of novel therapeutic strategy based on the molecular mechanism
    • 批准号:
      21592045
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2009
    • 负责人:
      MIYAKE Hideaki
    • 依托单位:
    海外基金