Investigation of epigenetic factors in the pathogenesis of glucocorticoid-induced glaucoma
Investigation of epigenetic factors in the pathogenesis of glucocorticoid-induced glaucoma
批准号:
21592239
负责人:
MATSUDA Akira
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The effects for dexamethasone(DEX) treatment for the genomic methylation status of human trabecular meshwork cells were analyzed by whole genome methylation array analysis. DEX treatment changed the expression level of 23 genes significantly. We analyzed the functional effect of genomic methylation/demethylation of RICS, RGS6 and GPR126 and found that the change of methylation status did affect not only the quantitative expression level but also qualitative expression pattern like the change of mRNA splicing.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
線維柱帯細胞のゲノムメチル化
小梁网细胞的基因组甲基化
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[松田彰, 他]
通讯作者:
他
デキサメサゾンによるヒト培養線維柱帯細胞のゲノムメチル化状態の変化
地塞米松引起的培养人小梁网细胞基因组甲基化状态的变化
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[松田彰, 海老原伸行, 村上晶]
通讯作者:
村上晶
Murakami A. Functional Roles of Thymic Stromal Lymphopoietin for Chronic Allergic Keratoconjunctivitis
Murakami A. 胸腺基质淋巴细胞生成素对慢性过敏性角结膜炎的功能作用
DOI:
--
发表时间:
2010
期刊:
Invest Ophthalmol
影响因子:
--
作者:
[Matsuda A, Ebihara N, Yokoi N, Kawasaki S, Tanioka H, Inatomi T, de Waal Malefyt R, Hamuro J, Kinoshita S]
通讯作者:
Kinoshita S
Th2サイトカイン環境は結膜繊維芽細胞のコラーゲンゲル収縮能を増加させる
Th2细胞因子环境增加结膜成纤维细胞的胶原凝胶收缩力
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[松田彰, 海老原伸行, 村上晶]
通讯作者:
村上晶
Two novel mutations identified in three Japanese gelatinous drop-like corneal dystrophy families
在三个日本凝胶状水滴样角膜营养不良家族中发现了两种新突变
DOI:
--
发表时间:
2011
期刊:
Mol Vis
影响因子:
2.2
作者:
[Nakatsukasa M, Kawasaki S, et al]
通讯作者:
et al
共 11 条
Methods and methodology for utilising an archaeological site after excavation as cultural resources of the local community
-
批准号:16K03152
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.08万
-
财政年份:2016
-
负责人:MATSUDA Akira
-
依托单位:
Pathophysiological Analysis of Atopic Glaucoma
-
批准号:24592652
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.49万
-
财政年份:2012
-
负责人:MATSUDA Akira
-
依托单位:
Targeting of the nuclease-resistant functional oligonucleotides
-
批准号:23249008
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$30.62万
-
财政年份:2011
-
负责人:MATSUDA Akira
-
依托单位:
Investigation into the molecular mechanism of the resolution of glucocorticoid resistance in lymphoma.
-
批准号:23880009
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$2.08万
-
财政年份:2011
-
负责人:MATSUDA Akira
-
依托单位:
Development of multifunctional envelope-type nano device encapsulating highly nuclease resistant oligonucleotides
-
批准号:18109001
-
项目类别:Grant-in-Aid for Scientific Research (S)
-
资助金额:$69.22万
-
财政年份:2006
-
负责人:MATSUDA Akira
-
依托单位:
Design of Nucleosides Antitumor Agents
-
批准号:17016001
-
项目类别:Grant-in-Aid for Scientific Research on Priority Areas
-
资助金额:$28.8万
-
财政年份:2005
-
负责人:MATSUDA Akira
-
依托单位:
Basic Studies of Molecular Recognition by 4'-Thionucleic acids
-
批准号:15209003
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$26.46万
-
财政年份:2003
-
负责人:MATSUDA Akira
-
依托单位:
Synthesis of new functionalized nucleic acids by the pentaerythritol linker.
-
批准号:13470481
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$5.95万
-
财政年份:2001
-
负责人:MATSUDA Akira
-
依托单位:
Design of Nuclease-resistant Antisense Molecules Based on the X-ray Structures of Some Nucleases
-
批准号:11557186
-
项目类别:Grant-in-Aid for Scientific Research (B).
-
资助金额:$4.22万
-
财政年份:1999
-
负责人:MATSUDA Akira
-
依托单位:
A study on development of inhibitors for neuronal cell death
-
批准号:08557134
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$1.22万
-
财政年份:1996
-
负责人:MATSUDA Akira
-
依托单位:
Highly Stereoselective Synthesis of Bicyclic-sugar Adenosine Derivatives via Diels-Alder Reaction.
-
批准号:06453184
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.22万
-
财政年份:1994
-
负责人:MATSUDA Akira
-
依托单位:
Developmental Studies of Nucleosidic Anti-RNA Virus Drugs
-
批准号:01870091
-
项目类别:Grant-in-Aid for Developmental Scientific Research (B).
-
资助金额:$4.74万
-
财政年份:1989
-
负责人:MATSUDA Akira
-
依托单位:
Interactions Between Oligodeoxyribonucleotides and Their Utilizing Enzymes
-
批准号:63470124
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.99万
-
财政年份:1988
-
负责人:MATSUDA Akira
-
依托单位:
海外基金