Investigation into the molecular mechanism of the resolution of glucocorticoid resistance in lymphoma.
Investigation into the molecular mechanism of the resolution of glucocorticoid resistance in lymphoma.
批准号:
23880009
负责人:
MATSUDA Akira
金额:
$2.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In this research, a novel mechanism of induction of glucocorticoid resistance in lymphoma cells was proposed by analyses of factors that could modulate the expression of glucocorticoid receptors. Furthermore, it was confirmed that inhibition of NF-κB could restore glucocorticoid sensitivity, suggesting that it may be a new strategy for the treatment of lymphoma with glucocorticoid resistance.
期刊论文(49)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
蹄葉炎新規治療薬としてのNF-κB阻害剤の効果解析
NF-κB抑制剂治疗蹄叶炎的效果分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Nakatsukasa K, Suetomi Y, Naniwa Y, Ito D, Inoue N, Wakabayashi Y, Okamura H, Maeda K-I, Uenoyama Y, Tsukamura H, Matsuda F, Ohkura S, 松田彬]
通讯作者:
松田彬
リンパ球のグルココルチコイド感受性におけるスプライシング制御因子の役割
剪接调节因子在淋巴细胞糖皮质激素敏感性中的作用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[松田彬、田中あかね, 他]
通讯作者:
他
海藻の一種であるカジメに含まれるdieckolの肥満細胞に対する効果
海藻 Kajime 中所含的二烯酚对肥大细胞的影响
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[アン・キンネ, 田中あかね, 他]
通讯作者:
他
Involvement of daily metallic soap in skin conditions of patients with atopic dermatitis
每日使用金属皂对特应性皮炎患者皮肤状况的影响
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[宮田祥嗣, 伊藤良樹, 佐藤崇, 前原誠也, Tanaka A]
通讯作者:
Tanaka A
イヌ末梢血単核球における時計遺伝子の概日リズム解析
犬外周血单个核细胞时钟基因的昼夜节律分析
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[三浦弘嗣, 阿野嘉孝, 薬師寿治, 右田たい子, 茂木立志, 北潔, 松下一信, 大森啓太郎]
通讯作者:
大森啓太郎
共 26 条
Methods and methodology for utilising an archaeological site after excavation as cultural resources of the local community
-
批准号:16K03152
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.08万
-
财政年份:2016
-
负责人:MATSUDA Akira
-
依托单位:
Pathophysiological Analysis of Atopic Glaucoma
-
批准号:24592652
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.49万
-
财政年份:2012
-
负责人:MATSUDA Akira
-
依托单位:
Targeting of the nuclease-resistant functional oligonucleotides
-
批准号:23249008
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$30.62万
-
财政年份:2011
-
负责人:MATSUDA Akira
-
依托单位:
Investigation of epigenetic factors in the pathogenesis of glucocorticoid-induced glaucoma
-
批准号:21592239
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.08万
-
财政年份:2009
-
负责人:MATSUDA Akira
-
依托单位:
Development of multifunctional envelope-type nano device encapsulating highly nuclease resistant oligonucleotides
-
批准号:18109001
-
项目类别:Grant-in-Aid for Scientific Research (S)
-
资助金额:$69.22万
-
财政年份:2006
-
负责人:MATSUDA Akira
-
依托单位:
Design of Nucleosides Antitumor Agents
-
批准号:17016001
-
项目类别:Grant-in-Aid for Scientific Research on Priority Areas
-
资助金额:$28.8万
-
财政年份:2005
-
负责人:MATSUDA Akira
-
依托单位:
Basic Studies of Molecular Recognition by 4'-Thionucleic acids
-
批准号:15209003
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$26.46万
-
财政年份:2003
-
负责人:MATSUDA Akira
-
依托单位:
Synthesis of new functionalized nucleic acids by the pentaerythritol linker.
-
批准号:13470481
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$5.95万
-
财政年份:2001
-
负责人:MATSUDA Akira
-
依托单位:
Design of Nuclease-resistant Antisense Molecules Based on the X-ray Structures of Some Nucleases
-
批准号:11557186
-
项目类别:Grant-in-Aid for Scientific Research (B).
-
资助金额:$4.22万
-
财政年份:1999
-
负责人:MATSUDA Akira
-
依托单位:
A study on development of inhibitors for neuronal cell death
-
批准号:08557134
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$1.22万
-
财政年份:1996
-
负责人:MATSUDA Akira
-
依托单位:
Highly Stereoselective Synthesis of Bicyclic-sugar Adenosine Derivatives via Diels-Alder Reaction.
-
批准号:06453184
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.22万
-
财政年份:1994
-
负责人:MATSUDA Akira
-
依托单位:
Developmental Studies of Nucleosidic Anti-RNA Virus Drugs
-
批准号:01870091
-
项目类别:Grant-in-Aid for Developmental Scientific Research (B).
-
资助金额:$4.74万
-
财政年份:1989
-
负责人:MATSUDA Akira
-
依托单位:
Interactions Between Oligodeoxyribonucleotides and Their Utilizing Enzymes
-
批准号:63470124
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.99万
-
财政年份:1988
-
负责人:MATSUDA Akira
-
依托单位:
海外基金