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Molecular biological analysis for engineering of dental pulp tissues with normal immune systems

Molecular biological analysis for engineering of dental pulp tissues with normal immune systems
具有正常免疫系统的牙髓组织工程的分子生物学分析
批准号:
21592411
负责人:
KANEKO Tomoatsu
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
Molecular biological analysis was performed to engineer dental pulp tissues with normal immune systems in rat molar. First, I identify that resident macrophages are one of the key functions to manage during dental initiate dental pulp inflammation. Second, I demonstrate the two types of macrophage lineage cells in the engineered pulp tissues. These macrophage subpopulations distribute with regional variations and show different activation levels in different areas of engineered tissues to maintain the engineered dental pulp tissues. Taken together, these results strongly suggested a possibility to engineer dental pulp tissue with normal immune systems.
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DOI: 10.1016/j.brainres.2010.11.054
发表时间: 2011-01
期刊: Brain Research
影响因子: 2.9
作者: [Mitsuhiro Kaneko;T. Kaneko;R. Kaneko;Uraiwan Chokechanachaisakul;J. Kawamura;M. Sunakawa;T. Okiji;H. Suda]
通讯作者: Mitsuhiro Kaneko;T. Kaneko;R. Kaneko;Uraiwan Chokechanachaisakul;J. Kawamura;M. Sunakawa;T. Okiji;H. Suda
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Bcl-2基因在大鼠实验性根尖周炎中的表达分析
DOI: --
发表时间: 2011
期刊: 日本歯科保存学雑誌
影响因子: --
作者: [山中裕介, 金子友厚, 吉羽邦彦, 興地隆史]
通讯作者: 興地隆史
だれもが知っておきたいReference the Classic-歴史的論文への招待Endo[14]歯内療法における局所麻酔剤について
参考经典 - 大家都应该知道的远藤历史论文邀请函[14]关于牙髓治疗中的局麻药
DOI: --
发表时间: 2011
期刊: ザ・クインテッセンス
影响因子: --
作者: [Kitasako Y, Sadr A, Nikaido T, Tagami J, 森本泰宏, 金子友厚/興地隆史]
通讯作者: 金子友厚/興地隆史
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DOI: --
发表时间: 2011
期刊: Journal of Endodontics
影响因子: 4.2
作者: [Nakazaki, K., Kato, Y., Taguchi, T., Inayama, Y., Ishiguro, Y., Tsukuda, M., 金子友厚/興地隆史]
通讯作者: 金子友厚/興地隆史
70
    Establishment of dental pulp tissue engineering by using autologous dental pulp stem cells in rat molars
    Molecular biological analysis of biomarkers for angiogenesis to promote dental pulp tissue engineering
    • 批准号:
      24592862
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.33万
    • 财政年份:
      2012
    • 负责人:
      KANEKO Tomoatsu
    • 依托单位:
    Molecular Biological Analysis for the function of Dendritic Cells in Dental Pulps and Periapical Lesions
    • 批准号:
      18791393
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.37万
    • 财政年份:
      2006
    • 负责人:
      KANEKO Tomoatsu
    • 依托单位:
    海外基金