Higher biofunctional nano-surface modification for development of histocompatibility typed titanium implants

更高生物功能纳米表面修饰用于开发组织相容性钛植入物

• 批准号: 21592452
• 负责人: ABE Yasuhiko
• 金额: $ 2.91万
• 依托单位: Hiroshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21592452/
• 关键词: チタン; インプラント; 表面改質; Hydroxylapatite; β-tricalcium phosphate; SPR解析; ESCA分析; Tricalcium phosphate

Concerning titanium implant coated with hydroxyapatite, processing method to treat hydroxyapatite with 30% phosphoric acid for 10 minutes was established for modification of a nanostructured surface with a ratio of calcium to phosphorus analogous toβ-tricalcium phosphate. This higher biofunctional nano-surface modification could accelerate the proliferation and differentiation of osteoblast cells

对于羟基磷灰石涂层的钛植入物，建立了用30%磷酸处理羟基磷灰石10分钟的处理方法，以改性具有类似于β-磷酸三钙的钙磷比的纳米结构表面。这种具有较高生物功能的纳米表面修饰可以促进成骨细胞的增殖和分化

项目成果

Detection ofsynthetic RGDS(PO3H2) PA peptideadsorption using a titanium surfaceplasmon resonance(SPR) biosensor, Journal of Materials Science

使用钛表面等离子共振 (SPR) 生物传感器检测合成 RGDS(PO3H2) PA 肽吸附，材料科学杂志

• 发表时间: 2011
• 期刊: Materials in Medicine
• 作者: Abe;Y.;Hiasa;K.;Hirata;I. Abe;Y.;Hiasa;K.;Hirata;I.;Okazaki;Y.;Nogami;K.;Mizumachi;W.;Yoshida;Y.;Suzuki;K.;Okazaki;M. and Akagawa;Y.
• 通讯作者: Y.

Degree of immobilization of synthetic RGDS(PO_3H_2) PA peptides on titanium surfaces

合成 RGDS(PO_3H_2) PA 肽在钛表面的固定程度

• 发表时间: 2010
• 期刊: Dental Materials Journal
• 影响因子: 2.5
• 作者: Abe;Y.;Okazaki;Y.;Hiasa;K.;Hirata;I.;Yoshida;Y.;Taji;T.;Suzuki;K.;Okazaki;M.;Akagawa;Y
• 通讯作者: Y

Real time assessment of surface interactions with a titanium passivation layer by surface plasmon resonance.

• DOI: 10.1016/j.actbio.2011.11.025
• 发表时间: 2012-03
• 期刊: ACTA BIOMATERIALIA
• 影响因子: 9.7
• 作者: Hirata, Isao;Yoshida, Yasuhiro;Nagaoka, Noriyuki;Hiasa, Kyou;Abe, Yasuhiko;Maekawa, Kenji;Kuboki, Takuo;Akagawa, Yasumasa;Suzuki, Kazuomi;Van Meerbeek, Bart;Messersmith, Phillip B.;Okazaki, Masayuki
• 通讯作者: Okazaki, Masayuki

Detection of synthetic RGDS (PO3H2) PA peptide adsorption using a titanium surface plasmon resonance (SPR) biosensor

使用钛表面等离子共振 (SPR) 生物传感器检测合成 RGDS (PO3H2) PA 肽吸附

• DOI: 10.1007/s10856-010-4222-2
• 发表时间: 2011
• 期刊: Journal of Materials Science : Materials in Medicine
• 作者: Abe;Y.;Hiasa;K.;Hirata;I.;Okazaki;Y.;Nogami;K.;Mizumachi;W.;Yoshida;Y.;Suzuki;K.;Okazaki;M.;Akagawa;Y.
• 通讯作者: Y.