Response of irradiated tissue supporting implant prosthesis under the compressing force.

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The aim of this study was to estimate the response of the irradiated tissue added the compressing force. Mouse osteoblast-like cells were compressed directly after the irradiation, gene expression of apoptosis channel was examined. Activation of caspase significant increased with stronger radiation, and decreased with the compressed force. It was recognized that gene expression related to prevention of apoptosis were increased under the compressing force.