Response of irradiated tissue supporting implant prosthesis under the compressing force.

本研究的目的是估计辐照组织在压缩力作用下的反应。照射后直接压缩小鼠成骨样细胞，检测凋亡通道基因表达。caspase的活化随辐射强度的增加而增加，随压缩力的增加而降低。已经认识到，在挤压力下，与防止细胞凋亡相关的基因表达增加。

The aim of this study was to estimate the response of the irradiated tissue added the compressing force. Mouse osteoblast-like cells were compressed directly after the irradiation, gene expression of apoptosis channel was examined. Activation of caspase significant increased with stronger radiation, and decreased with the compressed force. It was recognized that gene expression related to prevention of apoptosis were increased under the compressing force.