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Testing the utility of rationally engineered recombinant collagen-like proteins for applications of bone regeneration with bone morphogenetic protein in tissue engineering.

Testing the utility of rationally engineered recombinant collagen-like proteins for applications of bone regeneration with bone morphogenetic protein in tissue engineering.
测试合理设计的重组类胶原蛋白在组织工程中骨形态发生蛋白的骨再生应用中的效用。
批准号:
21592520
负责人:
HATTORI Hisashi
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
We mapped the D4 domain of human collagen I as most critical for binding site of bone morphogenetic protein(BMP) and used this information to genetically engineer a collagen-like protein consisting of tandem repeats of the D4 domain(mD4 collagen). We proved recombinant human mD4 collagen-like protein had a potential for an efficient scaffold as same as other scaffolds materials for engineering of bone when combined with BMP.
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会议论文
機能性リコンビナントコラーゲンの基礎的研究第2報スキャフォールドとしての検討
功能性重组胶原蛋白的基础研究,第 2 部分作为支架的检验
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [服部宇, 浜村和紀, 木下一彦, 池野正幸, 渋谷英伸, 廣中克紀, 小田知生, 上田実]
通讯作者: 上田実
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Shibata K, Yoshimura Y, Kikuiri T, Hasegawa T, Taniguchi Y, Deyama Y, Suzuki K, Iida J., Hideki Ishii, 服部宇, Fumihiko Takeuchi, Koichi Nakamura, Hiroyuki Asano, 服部宇]
通讯作者: 服部宇
DOI: 10.11607/jomi.te09
发表时间: 2013-09
期刊: The International journal of oral & maxillofacial implants
影响因子: --
作者: [M. Ikeno;H. Hibi;K. Kinoshita;H. Hattori;M. Ueda]
通讯作者: M. Ikeno;H. Hibi;K. Kinoshita;H. Hattori;M. Ueda
DOI: 10.11607/jomi.te19
发表时间: 2013-11-01
期刊: INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS
影响因子: 2
作者: [Ikeno, Masayuki, Hibi, Hideharu, Ueda, Minoru]
通讯作者: Ueda, Minoru
6
    Testing the utility of rationally engineered human recombinant collagen-like proteins for applications in tissue engineering
    • 批准号:
      18592173
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.32万
    • 财政年份:
      2006
    • 负责人:
      HATTORI Hisashi
    • 依托单位:
    海外基金