An experimental study for development of real time diagnosis system for oral cancer treatment using nanobubbles and ultrasound

本研究的目的是开发一种基于纳米气泡和高频超声的口腔癌实时影像诊断系统。结果发现了以下问题：超声造影剂引起的晕眩，动脉搏动引起的图像模糊，以及肿瘤未成熟的血管生成的成像。另一方面，通过对血流中纳米气泡的四维动力学分析，可以提高诊断的准确性。针对这些问题，本研究对高频超声成像系统的硬件和软件进行了改进

The aim of the present study is to develop a real time imaging diagnosis system for oral cancer using nanobubbles and high-frequency ultrasound. As a result, the following problems were revealed, halation caused by the ultrasound contrast agent, blurring of the image caused by arterial pulsation, and imaging of the immature angiogenesis of the tumor. On the other hand, the diagnostic accuracy could be improved by analyzing the four-dimentional dynamics of nanobubbles in the blood flow. In this stu dy, to solve the problems, hardware and software of the high frequency-ultrasound imaging system were improved