Movement of unerupted permanent teeth into bone regenerated by octacalcium phosphate collagen composites

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The purpose of this study was to investigate whether Octacalcium phosphate (OCP)collagen composites (OCP/Col)could be applied to alveolar clefts with unerupted permanent teeth as an alternative to autogenous particulate cancellous bone grafts. In two-month-old beagle dogs, the lower deciduous second/third molar teeth were extracted and the tooth extraction sockets were filled with either OCP/Col or SS-tricalcium phosphate (SS-TCP). The permanent third/fourth premolars (P3/P4)erupted through all the OCP/Col-implanted sites, whereas P3 and P4 were completely impacted in some of the SS-TCP-implanted regions. These results suggest that OCP/Col may be clinically applicable as an alternative to autogenous bone graft.