Establishment of Peri-implantitis treatment using a dual-purpose graft and cell transplantation.
建立使用双重目的移植物和细胞移植的种植体周围炎治疗方法。
基本信息
- 批准号:21592629
- 负责人:
- 金额:$ 2.75万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2009
- 资助国家:日本
- 起止时间:2009 至 2011
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The purpose of the present study was to evaluate cell biocompatibility and decontamination effect using β-TCP air-abrasion and BMP-2-incorporated PLGA microcapsule. β-TCP air abrasion decontamination led to microscopically visible alterations of the implant surface, however, it seems have a good potential to remove cytotoxic bacterial components from titanium surfaces. BMP-2 encapsulation efficiency from PLGA microcapsules was 37.5%. BMP-2 incorporated PLGA microcapsule elevated alkaline phosphatase activity in preosteoblasts. These results obtained suggest that encapsulated BMP-2 induces bone regeneration on titanium surface after removing cytotoxic bacterial components by β-TCP air-abrasion.
本研究的目的是评价β-TCP空气磨损和BMP-2掺入的PLGA微囊的细胞生物相容性和去污效果。β-TCP空气磨损去污导致植入物表面的显微镜可见改变,但是,它似乎具有从钛表面去除细胞毒性细菌成分的良好潜力。PLGA微囊的BMP-2包封率为37.5%。BMP-2微囊化可提高前成骨细胞碱性磷酸酶活性。这些结果表明,在通过β-TCP空气磨损去除细胞毒性细菌组分后,包封的BMP-2诱导钛表面的骨再生。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Regenerative effect of basic fibroblast growth factor on periodontal healing in 2-wall intrabony defects in dogs
碱性成纤维细胞生长因子对犬二壁骨内缺损牙周愈合的再生作用
- DOI:
- 发表时间:2010
- 期刊:
- 影响因子:0
- 作者:Yoshinori Shirakata;Katsuyoshi Taniyama;Takehiko Yoshimoto;Motoharu Miyamoto;Naoshi Takeuchi;Takashi Matsuyama;Kazuyuki Noguchi;Yoshinori Shirakata
- 通讯作者:Yoshinori Shirakata
Effectable application of vascular endothelial growth factor to critical sized rat calvaria defects
- DOI:10.1016/j.tripleo.2009.09.010
- 发表时间:2010-02-01
- 期刊:
- 影响因子:0
- 作者:Yonamine, Yutaka;Matsuyama, Takashi;Noguchi, Kazuyuki
- 通讯作者:Noguchi, Kazuyuki
骨分化刺激したマウスiPS細胞のラット歯周組織欠損への移植
将经成骨分化刺激的小鼠 iPS 细胞移植到大鼠牙周组织缺损中
- DOI:
- 发表时间:2010
- 期刊:
- 影响因子:0
- 作者:迫田賢二;白方良典;中村利明;松山孝司;野口和行
- 通讯作者:野口和行
Involvement of the endocannabinoid system in periodontal healing
- DOI:10.1016/j.bbrc.2010.03.080
- 发表时间:2010-04-16
- 期刊:
- 影响因子:3.1
- 作者:Kozono, Sayaka;Matsuyama, Takashi;Maruyama, Ikuro
- 通讯作者:Maruyama, Ikuro
A method for improving the light intensity distribution in dental light-curing units.
一种改善牙科光固化装置中的光强度分布的方法。
- DOI:10.4012/dmj.2010-114
- 发表时间:2011
- 期刊:
- 影响因子:2.5
- 作者:H. Arikawa;Hideo Takahashi;Y. Minesaki;K. Muraguchi;T. Matsuyama;T. Kanie;S. Ban
- 通讯作者:S. Ban
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MATSUYAMA Takashi其他文献
MATSUYAMA Takashi的其他文献
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{{ truncateString('MATSUYAMA Takashi', 18)}}的其他基金
Elucidation of the molecular mechanism for highly active terminator regions in Saccharomyces cerevisiae
阐明酿酒酵母高活性终止子区域的分子机制
- 批准号:
25660071 - 财政年份:2013
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
The influence of bone formation by thrombomodulin in platelet rich plasma gel
富血小板血浆凝胶中血栓调节蛋白对骨形成的影响
- 批准号:
15592193 - 财政年份:2003
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Elucidation of new adhesion mechanism between neutrophils and gingival epithelial cells via thrombomodulin
通过血栓调节蛋白阐明中性粒细胞与牙龈上皮细胞之间的新粘附机制
- 批准号:
13672193 - 财政年份:2001
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Real-Tune 3D Shape Reconstruction, Visualization, Editing, and Coding for 3D Video
实时调整 3D 形状重建、可视化、编辑和 3D 视频编码
- 批准号:
13308017 - 财政年份:2001
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Understanding human intention and activities for versatile real-time human-machine-interactions
了解人类意图和活动以实现多功能实时人机交互
- 批准号:
13224051 - 财政年份:2001
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
Cooperative Distributed Image Understanding Systems
协作分布式图像理解系统
- 批准号:
08408010 - 财政年份:1996
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Developing High Precision Versatile Camera Systems by Multi-Image Integration
通过多图像集成开发高精度多功能相机系统
- 批准号:
07558047 - 财政年份:1995
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Parallel Image Understanding System on Recursive Torus Architecture
递归环面架构的并行图像理解系统
- 批准号:
05452359 - 财政年份:1993
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
Geometric Programming System
几何规划系统
- 批准号:
03452171 - 财政年份:1991
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for General Scientific Research (B)
Effects of Doxorubicin or OK-432 on Cancer cells during liver regeneration after two-thirds hepatectomy
阿霉素或 OK-432 对三分之二肝切除术后肝再生过程中癌细胞的影响
- 批准号:
03670630 - 财政年份:1991
- 资助金额:
$ 2.75万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)