Autonomous flowing tube system for chemical solution propelled by its self-energy

自能驱动的化学溶液自主流动管道系统

• 批准号: 21650041
• 负责人: MITSUBAYASHI Kohji
• 金额: $ 2.09万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21650041/
• 关键词: 化学エネルギー; 酵素; 反応セル; グルコース; 隔膜; 減圧; チューブ; 送液

Novel chemo-mechanical energy conversion device for glucose as blood sugar was constructed using a glucose oxidase immobilized membrane. And an autonomous flowing system for glucose solution was fabricated by applying the device to a reaction cell with some valves. As the results, the novel energy conversion device indicated a decompression behavior which has a linear relationship with the concentration of glucose. The flowing system streamed with glucose solution(approx. 25μl/min) by its self-energy successfully.

采用葡萄糖氧化酶固定化膜，构建了一种新型葡萄糖作为血糖的化学-机械能量转换装置。并将该装置应用于带有阀门的反应池，制备了葡萄糖溶液的自主流动系统。结果表明，新型能量转换装置具有与葡萄糖浓度成线性关系的减压行为。流动的系统中有葡萄糖溶液(大约。25μl/min)。

项目成果

Soft-MEMS glucose sensor with functional polymers

采用功能聚合物的 Soft-MEMS 葡萄糖传感器

• 发表时间: 2010
• 期刊: Journal of Photopolymer Science and Technology 23(2)
• 作者: Iguchi S;Chu MX;Takahashi D;Arakawa T;Kudo H;Mitsubayashi K
• 通讯作者: Mitsubayashi K

An autonomous drug-release system based on chemo-mechanical energy conversion for blood sugar control

基于化学-机械能转换的血糖控制自主药物释放系统

• 发表时间: 2010
• 作者: Munkhjargal Munkhbayar;et.al.
• 通讯作者: et.al.

Autonomous Biosensors & BioSystem with Organic Engine(Bio-energetic intelligent function using artificial active transportation)

自主生物传感器

• 发表时间: 2010
• 作者: 前川亮;金子寛彦;K. Mitsubayashi
• 通讯作者: K. Mitsubayashi

Kinetic Biosensors with Intelligent Visible Motions for Chemical Analytes

用于化学分析物的具有智能可见运动的动力学生物传感器

• 发表时间: 2009
• 作者: Y. Wakabayashi;T. Okamoto;K. Miyajima;D. Takahashi;T. Arakawa;H. Kudo;K. Mitsubayashi
• 通讯作者: K. Mitsubayashi

An autonomous drug release system based on chemo-mechanical energy conversion "Organic Engine" for feedback control of blood glucose.

• DOI: 10.1016/j.bios.2010.07.080
• 发表时间: 2010-12
• 期刊: Biosensors & bioelectronics
• 影响因子: 12.6
• 作者: Ryodai Kato;Munkhbayar Munkhjargal;D. Takahashi;T. Arakawa;H. Kudo;K. Mitsubayashi