The effects of PRP and LIPUS during tooth movement

PRP 和 LIPUS 在牙齿移动过程中的作用

• 批准号: 21792097
• 负责人: SATO Yuki
• 金额: $ 2.83万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21792097/
• 关键词: 歯科医矯正学; PRP; LIPUS; 歯の移動; 多血小板血漿; 破骨細胞

This study is to clarify the histological effects of PRP administration and LIPUS insonification during tooth movement of rats. PRP component: The number of platelet and white blood cell (monocyte) increased. The tooth movement in 3-day and 7-day PRP+LIPUS groups was significantly faster than other group. Osteoclast numbers of 3-day increased significantly. Proliferation of blood vessels was also found in both PRP group. Destroyed PDL were observed in PRP+LIPUS group. Histologically there is a possibility that PRP or LIPUS induced the metabolic activity in rats, and therefore, led to the promoted tooth movement. However, PRP combined LIPUS may reduced PDL.

本研究旨在阐明PRP给药和LIPUS辐照对大鼠牙齿移动过程中的组织学影响。PRP成分：血小板和白色血细胞（单核细胞）数量增加。PRP+LIPUS组3 d和7 d牙移动速度明显快于其他组。3天破骨细胞数量明显增加。PRP组和对照组均可见血管增生。PRP+LIPUS组PDL破坏。从组织学上看，PRP或LIPUS可能诱导了大鼠的代谢活动，从而促进了牙齿移动。但PRP联合LIPUS可减少PDL。