The influence of coaggregation for a volatile sulfide production of Fusobacterium

共聚对梭杆菌挥发性硫化物产生的影响

• 批准号: 21792153
• 负责人: FUKUI Makoto
• 金额: $ 2.75万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21792153/
• 关键词: 口臭; Fusobacterium nucleatum; 歯周病原細菌; 揮発性硫黄化合物; 揮発性硫化物; 共凝集

The aim of this study was to clarify the influence of coaggregation between Fusobacterium nucleatum, a periodont pathogenic bacteria, and other microorganisms for production of volatile sulfur compound (VSC) by F. nucleatum. The coaggregation reaction was observed between F. nucleatum and Porphyromonas gingivalis, and shown that the production of VSC was significantly enhanced by incubation with live P. gingivalis compared to incubation F. nucleatum solely. It was also observed that the gene expression of F. nucleatum enzyme related with VSC production was tended to be enhanced by incubation with live P.gingivalis together whereas no effect was shown when incubated with heat-killed microorganism or supernatant of medium of P.gingivalis.

本研究的目的是阐明牙周病原菌核梭杆菌与其他微生物共聚集对核梭杆菌产生挥发性硫化物(VSC)的影响。观察到核盘藻与牙龈卟啉单胞菌之间的共聚集反应，结果表明，与单独孵育核盘藻相比，与活菌孵育相比，核盘藻VSC的产生显著增加。与活菌共同孵育后，与VSC产生相关的核盘菌酶的基因表达有增强趋势，而与热灭活微生物或菌液上清液共同孵育则无明显影响。

项目成果

肺炎球菌抗原とDNAアジュバント経鼻投与による粘膜免疫応答の解析

鼻腔给予肺炎球菌抗原和 DNA 佐剂后粘膜免疫反应分析

• 发表时间: 2009
• 作者: バータルジャフツェルメグ;片岡宏介;福井誠;伊藤博夫
• 通讯作者: 伊藤博夫

唾液中サイトカイン測定の健康診査への応用に関する研究

唾液细胞因子测定在健康体检中的应用研究

• 发表时间: 2009
• 作者: 福井誠;万井正章;宇野賀津子;伊藤博夫
• 通讯作者: 伊藤博夫

Cytokine profile in human saliva and its relationship with that in blood

人类唾液中的细胞因子谱及其与血液中的细胞因子谱的关系

• 发表时间: 2010
• 作者: Lamont RJ;Verma R;Bainbridge B;Demuth D;Kuboniwa M;Yehia B;Eastman C;Rivera M;Bhattacharyya I;Kesavalu L.;In vivo Interaction of P. gingivalis with S;Mulyatno A. S.
• 通讯作者: Mulyatno A. S.

ヒト血中および唾液中の抗ホスホリルコリン抗体の存在実態

人类血液和唾液中存在抗磷酸胆碱抗体

• 发表时间: 2010
• 作者: Amano A;Takeuchi H;Furuta N;山本裕美子;片岡宏介;Amano A;Amano A;福井誠
• 通讯作者: 福井誠

Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus

• DOI: 10.1016/j.micinf.2010.04.013
• 发表时间: 2010-09-01
• 期刊: MICROBES AND INFECTION
• 影响因子: 5.8
• 作者: Takahashi, Etsuhisa;Kataoka, Kosuke;Kido, Hiroshi
• 通讯作者: Kido, Hiroshi