Elucidation of roles of essential trace metals in higher nervous activity
Elucidation of roles of essential trace metals in higher nervous activity
批准号:
21390185
负责人:
SAITO Takeshi
金额:
$11.56万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The aim of this study is to elucidate roles of trace elements, metal transporters and metallochaperone in the central nervous system. Our results indicate that reduction of Cu transporter Ctr1 but not MT induction is the primary cause of the inhibition of Cu absorption by excessive intake of Zn. Declines of syntheses of catecholamines and zinc concentrations were observed in the cerebral cortex of SAMP10 with aging. Cu-polyphenol induces apoptosis via CCS-XIAP degradation induced by incorporated Cu in PC12 cells
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1007/s10661-008-0487-z
发表时间:
2009-09-01
期刊:
ENVIRONMENTAL MONITORING AND ASSESSMENT
影响因子:
3
作者:
[Kido, Machiko, Yustiawati, Kurasaki, Masaaki]
通讯作者:
Kurasaki, Masaaki
Elucidation of the role of zinc, zinc-enzyme and tetrahydrobiopterin in the alteration of chatecholamine metabolism in the cerebral cortex with aging in senescence-accelerated mouse
阐明锌、锌酶和四氢生物蝶呤在加速衰老小鼠大脑皮层儿茶酚胺代谢变化中的作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Mady FM, Abou-Taleb AE, Khaled KA, Yamasaki K, Iohara D, Taguchi K, Anraku M, Hirayama F, Uekama K, Otagiri M., 掛山正心, Miyajima M et al.]
通讯作者:
Miyajima M et al.
Mechanism of toxicity on human vascular endothelial cells by humic acid obtained from tropical peatland
热带泥炭地腐殖酸对人体血管内皮细胞的毒性机制
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kihara, Y et al.]
通讯作者:
Y et al.
クルクミン・銅および同時添加により引き起こされる細胞死とその機構
姜黄素、铜同时添加引起的细胞死亡及其机制
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Yataro Daigo, Yusuke Nakamura, 掛山正心・遠山千春, 佐藤睦将]
通讯作者:
佐藤睦将
Dysfunction of neurogenic VIP-mediated relaxation in mouse distal colon with dextran sulfate sodium-induced colitis
右旋糖酐硫酸钠诱导的小鼠远端结肠神经源性 VIP 介导的舒张功能障碍
DOI:
--
发表时间:
2012
期刊:
Pharmacological Research
影响因子:
9.3
作者:
[Kato E., Yamane S., Nomura R., Matsumoto K, Tashima K., Horie S., Saito T., Fujino H., Murayama T.]
通讯作者:
Murayama T.
共 24 条
Construction of basic data in toxicological evaluation: single and drug combinations used whole blood
-
批准号:17K09278
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2017
-
负责人:SAITO Takeshi
-
依托单位:
Quantitative evaluation of effect of subsurface warming on production and consumption of greenhouse gases
-
批准号:26889015
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.75万
-
财政年份:2014
-
负责人:SAITO Takeshi
-
依托单位:
Simultaneous determination of aconitines, amanitin, and tetrodotoxin using LC-MSMS
-
批准号:25460878
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.16万
-
财政年份:2013
-
负责人:SAITO Takeshi
-
依托单位:
Eruption processes inferred from magnetic petrology of FeTi oxides
-
批准号:25870290
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
-
财政年份:2013
-
负责人:SAITO Takeshi
-
依托单位:
Numerical and Functional Analyses of Regulatory T Cells in Biliary Atresia.
-
批准号:24592692
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2012
-
负责人:SAITO Takeshi
-
依托单位:
Establishing a method to screen strong antioxidant substances from carotenoid-producing bacteria based on the feeding instinct of nematodes
-
批准号:23658115
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:SAITO Takeshi
-
依托单位:
Cohomology of algebraic varieties and Galois representations
-
批准号:22244001
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$12.4万
-
财政年份:2010
-
负责人:SAITO Takeshi
-
依托单位:
Development of evaluation methods for effects of environmental chemicals on the central nervous systems
-
批准号:22659120
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.07万
-
财政年份:2010
-
负责人:SAITO Takeshi
-
依托单位:
Cytokine profile in biliary atresia patients
-
批准号:21592273
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2009
-
负责人:SAITO Takeshi
-
依托单位:
Eruption processes inferred from magnetic petrology of FeTi oxides
-
批准号:21740327
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$3.0万
-
财政年份:2009
-
负责人:SAITO Takeshi
-
依托单位:
Simultaneous analysis of paraquat, glufosinate and organophaophate in biological fluid using solid-phase extraction
-
批准号:21590745
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.66万
-
财政年份:2009
-
负责人:SAITO Takeshi
-
依托单位:
Establishment of immortalized cells from patients with biliary atresia
-
批准号:19791307
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.36万
-
财政年份:2007
-
负责人:SAITO Takeshi
-
依托单位:
Ramification in arithmetic geometry
-
批准号:18340002
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.96万
-
财政年份:2006
-
负责人:SAITO Takeshi
-
依托单位:
Simultaneous determination of ephedrines, amphetamines, cocaine, cocaine metabolites, and opiates and interaction in the rat
-
批准号:17590585
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.9万
-
财政年份:2005
-
负责人:SAITO Takeshi
-
依托单位:
Elucidation of the mechanism of membrane transport, metallochaperone of essential trace metals related to central nervous activities
-
批准号:15390182
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.66万
-
财政年份:2003
-
负责人:SAITO Takeshi
-
依托单位:
Cohomological study of arithmetic varieties
-
批准号:14340002
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.27万
-
财政年份:2002
-
负责人:SAITO Takeshi
-
依托单位:
Galois representations arising from etale cohomology
-
批准号:11640013
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:1999
-
负责人:SAITO Takeshi
-
依托单位:
Development of the evaluative method for harmful effects of environmental pollutant on the neurotransmission and genetic transcription.
-
批准号:10557039
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.81万
-
财政年份:1998
-
负责人:SAITO Takeshi
-
依托单位:
Elucidation of the mechanism of membrane transport of metal ions in the central nervous system and the relation to brain function
-
批准号:10470093
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.02万
-
财政年份:1998
-
负责人:SAITO Takeshi
-
依托单位:
Arithmetic of algebraic varieties
-
批准号:09640011
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.6万
-
财政年份:1997
-
负责人:SAITO Takeshi
-
依托单位: