Cancer prevention study on the relationship of cancer stem cells biomarker and 8-nitroguanine in cancer tissues
Cancer prevention study on the relationship of cancer stem cells biomarker and 8-nitroguanine in cancer tissues
批准号:
21390195
负责人:
KAWANISHI Shosuke
金额:
$11.56万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
8-Nitroguanine was formed in Oct3/4-positive stem cells in S. haematobium-associated cystitis and cancer tissues. 8-Nitroguanine and stem cell marker glypican-3 was observed in Barrett's esophagus tissues. In conclusion, inflammation by various facters may increase the number of mutant stem cells, in which nitrative DNA damage occurs, leading to tumor development.
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The Role of iNOS-Mediated DNA Damage in Inflammation-Related Care inogenesis
iNOS 介导的 DNA 损伤在炎症相关护理发生中的作用
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[S. Kawanishi, S. Ohnishi, H. Saito, N. Suzuki, Y. Hiraku, M. Murata, Kawanishi S., Hiraku Y.]
通讯作者:
Hiraku Y.
炎症・再生医学事典
炎症与再生医学百科全书
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Li Y-Y, Wu Y, Tsuneyama K, Baba T, Mukaida N., 吉崎真理子, 森本純子]
通讯作者:
森本純子
DOI:
10.1155/2012/165879
发表时间:
2012
期刊:
Mediators of inflammation
影响因子:
4.6
作者:
[Thanan R, Murata M, Ma N, Hammam O, Wishahi M, El Leithy T, Hiraku Y, Oikawa S, Kawanishi S]
通讯作者:
Kawanishi S
寄生虫感染による幹様細胞における酸化・ニトロ化DNA損傷
寄生虫感染导致干细胞样细胞氧化和硝化 DNA 损伤
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Thanan Raynoo]
通讯作者:
Thanan Raynoo
DOI:
10.1007/s12199-010-0146-1
发表时间:
2010-04
期刊:
Environmental Health and Preventive Medicine
影响因子:
4.7
作者:
[C. Watanabe;Takashi Egami;K. Midorikawa;Y. Hiraku;S. Oikawa;S. Kawanishi;M. Murata]
通讯作者:
C. Watanabe;Takashi Egami;K. Midorikawa;Y. Hiraku;S. Oikawa;S. Kawanishi;M. Murata
共 34 条
Molecular epidemiological study on cholangio-carcinogenesis induced by liver fluke Opisthorchis viverrini in Thailand.
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批准号:21406019
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2009
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负责人:KAWANISHI Shosuke
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依托单位:
Development of the biomarker analysis system for evaluating the risk of carcinogenesis related to infection and inflammation
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批准号:18390179
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.13万
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财政年份:2006
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负责人:KAWANISHI Shosuke
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依托单位:
The mechanism for the formation of hotspots in relation to evaluation of carcinogenic risks of environmental chemicals
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批准号:15390187
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.66万
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财政年份:2003
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负责人:KAWANISHI Shosuke
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依托单位:
Molecular epidemiological study on the pathogenesis of cholangiocarcinoma caused by infection with liver flukes in Thailand
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批准号:15406027
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.58万
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财政年份:2003
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负责人:KAWANISHI Shosuke
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依托单位:
Development of evaluation system for cancer chemopreventive agents based on DNA damage inhibition and gene expression
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批准号:13557030
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.09万
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财政年份:2001
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负责人:KAWANISHI Shosuke
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依托单位:
Analysis of sequence-specific DNA damage by oxidative stress and prevention of cancer and aging
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批准号:12470084
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.9万
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财政年份:2000
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负责人:KAWANISHI Shosuke
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依托单位:
Evaluation of toxicity of environmental chemicals on the basis of their estrogenic activity and DNA-damaging ability and regional risk assessment
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批准号:11794019
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项目类别:Grant-in-Aid for University and Society Collaboration
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资助金额:$7.68万
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财政年份:1999
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负责人:KAWANISHI Shosuke
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依托单位:
The method of safety evaluation of chemopreventive agents based on the ability of damaging human genes
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批准号:10557040
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$7.62万
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财政年份:1998
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负责人:KAWANISHI Shosuke
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依托单位:
Mechanisms of DNA damage induced by environmental factors and cancer chemoprevention
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批准号:09470101
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.19万
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财政年份:1997
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负责人:KAWANISHI Shosuke
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依托单位:
Oxygen radical formation and DNA damage induced by metal compounds in relation to carcinogenicity
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批准号:06454227
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.8万
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财政年份:1994
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负责人:KAWANISHI Shosuke
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依托单位:
Analysis of damage to human genes for estimating the carcinogenicity of environmental chemicals
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批准号:06557028
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$7.3万
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财政年份:1994
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负责人:KAWANISHI Shosuke
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依托单位:
Analysis of DNA damage in cultured cells induced by Ames test-negative carcinogens.
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批准号:04454216
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.48万
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财政年份:1992
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负责人:KAWANISHI Shosuke
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依托单位:
Development of DNA damage-analyzing method for estimating genotoxicity of chemical substances
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批准号:63870027
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$3.65万
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财政年份:1988
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负责人:KAWANISHI Shosuke
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依托单位:
Reactivities of chemical substances with human protooncogene in application to screening of carcinogenicity
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批准号:62570228
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1987
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负责人:KAWANISHI Shosuke
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依托单位: