A comprehensive transcriptome analysis of humanized mouse liver using ultra high density cDNA micro array
A comprehensive transcriptome analysis of humanized mouse liver using ultra high density cDNA micro array
批准号:
21390229
负责人:
CHAYAMA Kazuaki
金额:
$11.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
我们利用人肝细胞嵌合小鼠,用高密度微阵列技术研究了乙型和丙型肝炎病毒持续感染的机制。干扰素刺激基因的诱导被两种病毒部分抑制,提示这两种病毒抑制干扰素刺激基因诱导的机制不同。
英文摘要
We investigated a mechanism of continuous infection of hepatitis B and hepatitis C virus with high density microarray using human hepatocyte chimeric mice. Induction of interferon stimulated genes were partially inhibited by each of the two viruses suggesting that these viruses inhibit induction of interferon stimulated genes with different mechanisms
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Achievement of Sustained Viral Response after Switching Treatment from Pegylated Interferon alpha-2b to alpha-2a and Ribavirin in Patients with Recurrence of Hepatitis C Virus Genotype 1 Infection after Liver Transplantation : A Case Report
肝移植后丙型肝炎病毒基因型 1 感染复发患者从聚乙二醇干扰素 α-2b 转为 α-2a 和利巴韦林治疗后获得持续病毒缓解:病例报告
DOI:
10.1159/000328661
发表时间:
2011
期刊:
Intervirology (Elpub 25 Aug.)
影响因子:
--
作者:
[Kawaoka T, Hiraga N, Takahashi S, Takaki S, Tsuge M, Nagaoki Y, Hashimoto Y, Katamura Y, Muki D, Hiramatsu A, Waki K, Imamura M, Kawakami Y, Aikata H, Ochi H, Tashiro H, Ohdan H, Chayama K]
通讯作者:
Chayama K
Cutaneous complications after transcatheter arterial treatment for hepat ocellular carcinoma via the internal mammary artery : how to avoid this complication
经乳内动脉经导管动脉治疗肝眼细胞癌后的皮肤并发症:如何避免这种并发症
DOI:
10.1007/s11604-011-0559-9
发表时间:
2011
期刊:
Jpn J Radiol
影响因子:
2.1
作者:
[Kajiwara K, Kakizawa H, Takeuchi N, Toyota N, Hieda M, Ishikawa M, Tanitame K, Tani G, Suzuki T, Fujikawa K, Aikata H, Chayama K, Awai K]
通讯作者:
Awai K
3cm以下単発、Child A肝細胞癌に対する肝切除とラジオ波焼灼療法の比較
肝切除与射频消融治疗小于3 cm单发Child A肝细胞癌的比较
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[脇浩司, 相方浩, 長沖祐子, 石田友希, 橋本義政, 片村嘉男, 河岡友和, 高木慎太郎, 平松憲, 今村道雄, 川上由育, 高橋祥一, 田代裕尊, 大段秀樹, 茶山一彰]
通讯作者:
茶山一彰
NAFLDの肝線維化と血小板数の関係について
关于NAFLD中肝纤维化与血小板计数的关系
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[石飛朋和, 兵庫秀幸, 鍋島由宝, 石田友希,茶山一彰]
通讯作者:
石田友希,茶山一彰
B型慢性肝炎の治療
慢性乙型肝炎的治疗
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Shimizu K, Makita H, Konno S, Nishimura M, et al., 茶山一彰]
通讯作者:
茶山一彰
共 108 条
Identification of SNPs on mature micro RNA to analyze origin of miRNA
-
批准号:25670369
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2013
-
负责人:CHAYAMA Kazuaki
-
依托单位:
Analysis of unknown pathogen using human hepatocyte chimeric mouseand massive parallel sequencing
-
批准号:24659368
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2012
-
负责人:CHAYAMA Kazuaki
-
依托单位:
Generation of a mouse model that shows specific features of human diseases.
-
批准号:22659147
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.07万
-
财政年份:2010
-
负责人:CHAYAMA Kazuaki
-
依托单位:
Production of interferon stimulated gene library and screening of new therapeutic drug for hepatitis viruses
-
批准号:18390218
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.35万
-
财政年份:2006
-
负责人:CHAYAMA Kazuaki
-
依托单位:
Specification of the factor in a liver cell required for multiplication of hepatitis C virus
-
批准号:13670521
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:2001
-
负责人:CHAYAMA Kazuaki
-
依托单位:
Analysis of lamivudine resistance acquisition by hepatitis B virus.
-
批准号:13557049
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.32万
-
财政年份:2001
-
负责人:CHAYAMA Kazuaki
-
依托单位:
Detection of drug resistant mutant hepatitis B virus strain and its clinical application.
-
批准号:10670524
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:1998
-
负责人:CHAYAMA Kazuaki
-
依托单位:
Interferon resistance of hepatitis C virus
-
批准号:06670595
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$0.26万
-
财政年份:1994
-
负责人:CHAYAMA Kazuaki
-
依托单位:
海外基金