Establishment of substrates exploration of protozoan enzymes associated with invasion into host cells
Establishment of substrates exploration of protozoan enzymes associated with invasion into host cells
批准号:
21780263
负责人:
KATO Kentaro
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
We have got some results that protozoa enzymes including protein kinases take parts in the important signal transductions for parasites to transfer from a stage to the next stage by analyzing the substrates and functions of enzymes relating with calcium signaling in their complicated life cycles. These results lead to the new anti-protozoan drug developments to block the protozoa-specific life cycle by inhibiting the functions of the important protozoan enzymes in the stage transfer.
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Bovine viral diarrhea virus nonstructural protein 5A interacts with NIK and IKKβ-binding protein (NIBP).
牛腹泻病毒病毒非结构蛋白 5A 与 NIK 和 IKKβ 结合蛋白 (NIBP) 相互作用。
DOI:
--
发表时间:
2010
期刊:
J Gen Virol. 91
影响因子:
--
作者:
[Zahoor MA, Yamane, D, Mohamed YM, Suda Y, Kobayashi K, Kato K, Tohya T, Akashi H.]
通讯作者:
Akashi H.
マラリア原虫独自酵素によるその巧妙なライフサイクルコントロール
利用疟疾寄生虫自身的酶巧妙地控制其生命周期
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[杉達紀, 加藤健太郎, 小林郷介, 明石博臣, 加藤健太郎]
通讯作者:
加藤健太郎
DOI:
10.1016/j.antiviral.2009.11.007
发表时间:
2010-02-01
期刊:
ANTIVIRAL RESEARCH
影响因子:
7.6
作者:
[Azab, Walid, Tsujimura, Koji, Akashi, Hiroomi]
通讯作者:
Akashi, Hiroomi
Activation of extracellular signal-regulated kinase in MDBK cells infected with bovine viral diarrhea virus
牛病毒性腹泻病毒感染MDBK细胞中细胞外信号调节激酶的激活
DOI:
--
发表时间:
2009
期刊:
Arch Virol 154
影响因子:
--
作者:
[Yamane D, Zahoor MA, Mohamed YM, Azab W, Kato K, Tohya Y, Akashi H.]
通讯作者:
Akashi H.
マラリア原虫のPfCDPK4の有性生殖期における発現解析
疟原虫PfCDPK4在有性生殖阶段的表达分析
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[加藤健太郎, 小林郷介, 杉達紀, 遠矢幸伸, 明石博臣]
通讯作者:
明石博臣
共 23 条
Establishment of amino acid-capped metal nanoparticle for enhancing anti-protozoan activity
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批准号:19K22940
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
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财政年份:2019
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负责人:KATO Kentaro
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依托单位:
Comprehensive analyses in components of Toxoplasma dormant parasites.
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批准号:17H03913
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.32万
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财政年份:2017
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负责人:KATO Kentaro
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依托单位:
Ecology between livestock and infectious microbes to maintain food circulation
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批准号:16KT0141
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2016
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负责人:KATO Kentaro
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依托单位:
Regulation mechanisms of pathogenicity of intestinal protozoa
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批准号:16K08761
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2016
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负责人:KATO Kentaro
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依托单位:
A study on signal modulation theory for quantum stream cipher
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批准号:15K06082
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2015
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负责人:KATO Kentaro
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依托单位:
Identification of trigger factor for the differentiation of Toxoplasma bradyzoite
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批准号:25670199
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:KATO Kentaro
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依托单位:
Roles of cabohydrates in protozoan infection
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批准号:24688032
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$17.06万
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财政年份:2012
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负责人:KATO Kentaro
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依托单位:
Elucidation of malaria erythrocyte invasion system using stem cell techonology
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批准号:23659208
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2011
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负责人:KATO Kentaro
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依托单位:
Elucidation of the carbohydrate recognization mechanisms by intestinal protozoa using MUC2 glycopeptides
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批准号:23790460
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
-
财政年份:2011
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负责人:KATO Kentaro
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依托单位:
Development of glycopeptide array aiming for diagnosis of infectious diseases
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批准号:20890007
-
项目类别:Grant-in-Aid for Young Scientists (Start-up)
-
资助金额:$2.06万
-
财政年份:2008
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负责人:KATO Kentaro
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依托单位:
Characterization of protozoan protein kinases aiming at the new anti-protozoan strategy
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批准号:18688017
-
项目类别:Grant-in-Aid for Young Scientists (A)
-
资助金额:$18.55万
-
财政年份:2006
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负责人:KATO Kentaro
-
依托单位:
海外基金