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Design and implementation of a novel mapping technique for single-nucleotide polymorphism genotypes using Textile Plot

Design and implementation of a novel mapping technique for single-nucleotide polymorphism genotypes using Textile Plot
使用 Textile Plot 设计和实现单核苷酸多态性基因型的新型作图技术
批准号:
21790342
负责人:
KUMASAKA Natsuhiko
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

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中文摘要
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英文摘要
Textile Plot is a novel visualization technique and multivariate data analysis tool in statistics. We applied it to single-nucleotide polymorphism genotype data to develop a novel mapping technique of linkage disequilibrium, selection footprints and disease genes. We provided a population genetic perspective of the plot along with a software environment implemented in JAVA language. We also performed disease gene mappings in an association study of chronic hepatitis B and a comparative study of Crohn's disease and ulcerative colitis in Japanese.
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会议论文
LD mapping of disease gene and haplotype analysis on textile plot
纺织图上疾病基因的 LD 作图和单倍型分析
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kumasaka, N., Kamatani, N.]
通讯作者: N.
HLA-Cw*1202-B*5201-DRB1*1502 haplotype confers distinct effects on ulcerative colitis and Crohn's disease in Japanese.
HLA-Cw*1202-B*5201-DRB1*1502 单倍型对日本人的溃疡性结肠炎和克罗恩病具有独特的作用。
DOI: --
发表时间: 2011
期刊: Gastroenterology(peer review, accepted : June 6, 2011) doi:10.1053/gastro.(in press.)
影响因子: --
作者: [Okada, Y., Yamazaki, K., Umeno, J., Takahashi, A., Kumasaka, N., Ashikawa, K., Aoi, T., Takazoe, M., Matsui, T., Hirano, A., Matsumoto, T., Kamatani, N., Nakamura, Y., Yamamoto, K.Kubo, M.]
通讯作者: M.
DOI: 10.1371/journal.pone.0010207
发表时间: 2010-04-27
期刊: PloS one
影响因子: 3.7
作者: [Kumasaka N, Nakamura Y, Kamatani N]
通讯作者: Kamatani N
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
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