A new inner ear treatment utilizing anti TNF-α antibody

利用抗 TNF-α 抗体的新型内耳治疗方法

• 批准号: 21791587
• 负责人: FUTAI Kazunori
• 金额: $ 2.75万
• 依托单位: Hirosaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21791587/
• 关键词: TNF-α; 鼓室内投与; 内耳再生; 自己血清点耳

It was thought that the whole body administration of the anti-TNF-α antibody to which the side effect happened frequently was improper as the mode of administration to the inner ear hair cells interruption, and the most effective technique was the direct administering to the inner ear by way of the fenestra rotunda. It was suggested that the transtympanic administration with an endoscope made the delivery of medicines into inner ears most easy and surely.

作者认为，作为干扰内耳毛细胞的给药方式，抗肿瘤坏死因子-α抗体的全身给药是不合适的，经圆窗直接给药是最有效的方法。提示内窥镜下经鼓室给药使内耳给药更容易、更可靠。

项目成果

ホームページ等。

主页等

ENDOSCOPIC TRANSTYMPANIC SURGERY IN THE TREATMENT OF CONDUCTIVE HEARING LOSS, CONGENITAL CHOLESTEATOMA AND ADHESIVE OTITIS MEDIA

内镜经鼓膜手术治疗传导性听力损失、先天性胆脂瘤和粘连性中耳炎

• 发表时间: 2009
• 作者: Takahara M;Kishibe K;Nagato T;Moriai S;Ishii H;Katayama A;Harabuchi Y;長岐孝彦;二井一則;Kazunori Futai;二井一則;Kazunori Futai
• 通讯作者: Kazunori Futai

Endoscopic transtynmpanic surgery in the treatment of conductive hearing loss, congenital cholesteatoma and adhesive otitis media

内镜经鼓膜手术治疗传导性听力损失、先天性胆脂瘤和粘连性中耳炎

• 发表时间: 2009
• 作者: Takahara M;Kishibe K;Nagato T;Moriai S;Ishii H;Katayama A;Harabuchi Y;長岐孝彦;二井一則;Kazunori Futai
• 通讯作者: Kazunori Futai

当院における自己血清点耳療法の使用経験

我院使用自体血清滴耳疗法的体会

• 发表时间: 2010
• 作者: Takahara M;Kishibe K;Nagato T;Moriai S;Ishii H;Katayama A;Harabuchi Y;長岐孝彦;二井一則
• 通讯作者: 二井一則

外来経過中に人工耳小骨によるアブミ骨底板骨折を発症した1症例

门诊人工耳小骨致镫骨基板骨折一例。

• 发表时间: 2009
• 作者: Takahara M;Kishibe K;Nagato T;Moriai S;Ishii H;Katayama A;Harabuchi Y;長岐孝彦;二井一則;Kazunori Futai;二井一則
• 通讯作者: 二井一則