The influence of immediate loading on bone around titanium implants with different surface topographies

即刻加载对不同表面形貌钛种植体周围骨的影响

• 批准号: 21791876
• 负责人: SATO Naoko
• 金额: $ 2.75万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21791876/
• 关键词: 早期荷重; インプラント表面性状; 骨結合

To examine the interactive effects of mechanical loading and titanium surface topography on bone formation around immediately loaded implants, bone with loaded soomth(Sm) and acid-etched (AE) implants in rats were scanned by micro-CT system and removable torque test was performed. The loaded AE implants showed significantly decreased in bone mineral density of cortical bone at week 4 and contact surface area between cortical bone and the implant at week 2 compared to those for unloaded AE implants. The removable torque values for loaded Sm implants at week 1 was significantly lower than that for unloaded Sm implants although the loading didn't affect the biomechanical strength for AE implants. These suggested that different surface topography differently affected bone responses around immediately loaded implants.

为探讨机械载荷和钛表面形貌对即刻加载种植体周围骨形成的交互作用，采用micro-CT扫描系统对加载Somth（Sm）和酸蚀（AE）种植体的大鼠骨进行扫描，并进行可拆卸扭矩试验。与未加载的AE种植体相比，加载的AE种植体在第4周时皮质骨的骨矿物质密度和第2周时皮质骨与种植体之间的接触表面积显著降低。加载的Sm种植体在第1周的可移除扭矩值显着低于未加载的Sm种植体，但加载并不影响AE种植体的生物力学强度。这表明不同的表面形貌对即刻加载种植体周围的骨反应有不同的影响。

项目成果

Age-dependent Degradation of the Protein Adsorption Capacity of Titanium

• DOI: 10.1177/0022034509339567
• 发表时间: 2009-07-01
• 期刊: JOURNAL OF DENTAL RESEARCH
• 影响因子: 7.6
• 作者: Hori, N.;Att, W.;Ogawa, T.
• 通讯作者: Ogawa, T.

N-acetyl cysteine alleviate cytotoxity of bone substitute

N-乙酰半胱氨酸减轻骨替代物的细胞毒性

• 发表时间: 2010
• 期刊: J Dental Res. 89
• 作者: Yamada M;Ueno T;Minamikawa T;Sato N;Ogawa T
• 通讯作者: Ogawa T

N-acetyl cysteine alleviates cytotoxity of bone substitute.

N-乙酰半胱氨酸减轻骨替代物的细胞毒性。

• 发表时间: 2010
• 期刊: J Dental Research
• 作者: Yamada M;Ueno T;Minamikawa;Sato N;Ogawa.T
• 通讯作者: Ogawa.T