BRAK is a new type marker for development of tailor made medicine in head and neck squamous cell carcinoma.
BRAK 是一种新型标记物,用于开发头颈鳞状细胞癌定制药物。
基本信息
- 批准号:21792037
- 负责人:
- 金额:$ 2.83万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Young Scientists (B)
- 财政年份:2009
- 资助国家:日本
- 起止时间:2009 至 2010
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
BRAK is not expressed or negligible level in head and neck squamous cell carcinoma. We cleared that methylation of BRAK promoter regulates the expression of BRAK as a negative regulator.
BRAKE在头颈部鳞状细胞癌中不表达或表达水平可忽略不计。我们明确了BRAK启动子甲基化作为负调控因子调控BRAK的表达。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Expression of BRAK/CXCL14 is associated with antitumor efficacy of gefitinib in head and neck squamous cell carcinoma.
BRAK/CXCL14 的表达与吉非替尼在头颈鳞状细胞癌中的抗肿瘤功效相关。
- DOI:
- 发表时间:2009
- 期刊:
- 影响因子:0
- 作者:Shigeyuki Ozawa;Yasumasa Kato;Shin Ito;Reika Komori;Kenji Suzuki;Keiichi Tsukinoki;Yojiro Maehata;Takahide Taguchi;Yukari Imagawa-Ishiguro;Mamoru Tsukuda;Eiro Kubota;Ryu-Ichiro Hata
- 通讯作者:Ryu-Ichiro Hata
Chemokine BRAK/CXCL14 is a multifunctional tumor suppressor.
趋化因子 BRAK/CXCL14 是一种多功能肿瘤抑制因子。
- DOI:
- 发表时间:2010
- 期刊:
- 影响因子:0
- 作者:Hata R;Izukuri K;Suzuki K;Yajima N;Ozawa S;Ito S;Kubota E
- 通讯作者:Kubota E
BRAK/CXCL14 expression in oral carcinoma cells completely suppresses tumor cell xenografts in SCID mouse
- DOI:10.2220/biomedres.30.315
- 发表时间:2009-10-01
- 期刊:
- 影响因子:1.2
- 作者:Ozawa, Shigeyuki;Kato, Yasumasa;Hata, Ryu-Ichiro
- 通讯作者:Hata, Ryu-Ichiro
Restoration of BRAK/CXCL14 gene expression by gefitinib is associated with antitumor efficacy of the drug in head and neck squamous cell carcinoma
- DOI:10.1111/j.1349-7006.2009.01281.x
- 发表时间:2009-11-01
- 期刊:
- 影响因子:5.7
- 作者:Ozawa, Shigeyuki;Kato, Yasumasa;Hata, Ryu-Ichiro
- 通讯作者:Hata, Ryu-Ichiro
Chemokine BRAK stimulates apoptosis elicited by gefitinib in oral squamous cell carcinoma
趋化因子 BRAK 刺激吉非替尼在口腔鳞状细胞癌中引起的细胞凋亡
- DOI:
- 发表时间:2009
- 期刊:
- 影响因子:0
- 作者:Ito S;Ozawa S;Shiiki N;Tsukinoki K;Kubota E;Kato Y;Taguchi T;Imagawa-Ishiguro Y;Tsukuda M;Hata R
- 通讯作者:Hata R
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OZAWA Shigeyuki其他文献
OZAWA Shigeyuki的其他文献
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{{ truncateString('OZAWA Shigeyuki', 18)}}的其他基金
Combination chemotherapy for head and neck squamous cell carcinoma
头颈鳞状细胞癌的联合化疗
- 批准号:
19791553 - 财政年份:2007
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
相似海外基金
Head and neck cancer suppression strategy targeting cancer stem cells of multistep tumor suppressor molecule CXCL14 / BRAK
多步抑癌分子CXCL14/BRAK靶向癌症干细胞的头颈癌抑制策略
- 批准号:
16K11736 - 财政年份:2016
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Clinical application of BRAK that is anti-angiogenic agent
抗血管生成剂BRAK的临床应用
- 批准号:
15K20567 - 财政年份:2015
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
A way to molecular targetting preventive medicine:Suppression of lung metastasis of cancer by BRAK gene
分子靶向预防医学之路:BRAK基因抑制癌症肺转移
- 批准号:
15K15697 - 财政年份:2015
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Search of transcription factor for BRAK by using new method in Head and neck carcinoma
利用新方法寻找头颈癌中BRAK转录因子
- 批准号:
25861982 - 财政年份:2013
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Investigation of cancer therapeutic method without side effects: Suppression mechanisms of cancer metastasis on the lung by CXCL14/BRAK
无副作用癌症治疗方法的研究:CXCL14/BRAK抑制癌症肺部转移的机制
- 批准号:
25293384 - 财政年份:2013
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Development of a new oral cancer treatment via regulation of the anti-tumor factor BRAK expression with DNA methylation inhibitors.
通过用 DNA 甲基化抑制剂调节抗肿瘤因子 BRAK 表达来开发新的口腔癌治疗方法。
- 批准号:
25463101 - 财政年份:2013
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Research and development of anti-tumor therapy by anti-tumor chemokine BRAK
抗肿瘤趋化因子BRAK抗肿瘤治疗的研究进展
- 批准号:
23792390 - 财政年份:2011
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Exhaustive analysis of the antitumor effect by suppression of vascularization that is a function of chemokine BRAK
详尽分析趋化因子 BRAK 所发挥的抑制血管化作用的抗肿瘤作用
- 批准号:
23792156 - 财政年份:2011
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Analysis of promoter of human BRAK/CXCL14, a tumor suppressor
人肿瘤抑制因子 BRAK/CXCL14 启动子分析
- 批准号:
22792023 - 财政年份:2010
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
CXCL14/BRAK is a multifunctional tumor suppressor
CXCL14/BRAK是一种多功能肿瘤抑制因子
- 批准号:
22390353 - 财政年份:2010
- 资助金额:
$ 2.83万 - 项目类别:
Grant-in-Aid for Scientific Research (B)