BRAK is a new type marker for development of tailor made medicine in head and neck squamous cell carcinoma.
BRAK is a new type marker for development of tailor made medicine in head and neck squamous cell carcinoma.
批准号:
21792037
负责人:
OZAWA Shigeyuki
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
BRAK在头颈部鳞状细胞癌中不表达或表达水平可忽略。我们明确了BRAK启动子的甲基化作为负调控因子调节BRAK的表达。
英文摘要
BRAK is not expressed or negligible level in head and neck squamous cell carcinoma. We cleared that methylation of BRAK promoter regulates the expression of BRAK as a negative regulator.
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Expression of BRAK/CXCL14 is associated with antitumor efficacy of gefitinib in head and neck squamous cell carcinoma.
BRAK/CXCL14 的表达与吉非替尼在头颈鳞状细胞癌中的抗肿瘤功效相关。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Shigeyuki Ozawa, Yasumasa Kato, Shin Ito, Reika Komori, Kenji Suzuki, Keiichi Tsukinoki, Yojiro Maehata, Takahide Taguchi, Yukari Imagawa-Ishiguro, Mamoru Tsukuda, Eiro Kubota, Ryu-Ichiro Hata]
通讯作者:
Ryu-Ichiro Hata
Chemokine BRAK/CXCL14 is a multifunctional tumor suppressor.
趋化因子 BRAK/CXCL14 是一种多功能肿瘤抑制因子。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Hata R, Izukuri K, Suzuki K, Yajima N, Ozawa S, Ito S, Kubota E]
通讯作者:
Kubota E
DOI:
10.2220/biomedres.30.315
发表时间:
2009-10-01
期刊:
BIOMEDICAL RESEARCH-TOKYO
影响因子:
1.2
作者:
[Ozawa, Shigeyuki, Kato, Yasumasa, Hata, Ryu-Ichiro]
通讯作者:
Hata, Ryu-Ichiro
DOI:
10.1111/j.1349-7006.2009.01281.x
发表时间:
2009-11-01
期刊:
CANCER SCIENCE
影响因子:
5.7
作者:
[Ozawa, Shigeyuki, Kato, Yasumasa, Hata, Ryu-Ichiro]
通讯作者:
Hata, Ryu-Ichiro
Chemokine BRAK stimulates apoptosis elicited by gefitinib in oral squamous cell carcinoma
趋化因子 BRAK 刺激吉非替尼在口腔鳞状细胞癌中引起的细胞凋亡
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Ito S, Ozawa S, Shiiki N, Tsukinoki K, Kubota E, Kato Y, Taguchi T, Imagawa-Ishiguro Y, Tsukuda M, Hata R]
通讯作者:
Hata R
Combination chemotherapy for head and neck squamous cell carcinoma
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批准号:19791553
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.25万
-
财政年份:2007
-
负责人:OZAWA Shigeyuki
-
依托单位:
海外基金