Queensland high throughput structural biology screening facility

昆士兰高通量结构生物学筛选设施

• 批准号: LE0347585
• 负责人: Prof Jennifer Martin
• 金额: $ 21.84万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2004-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0347585
• 关键词: Queensland; throughput; structural; biology; screening

Structural biology is undergoing a worldwide revolution, enabling an enormous acceleration in the rate of protein structure determination. Australia currently lacks facilities to enable this high throughput approach to structural biology. We plan to establish a facility that addresses this deficiency and will enable the structure determination of hundreds of new proteins per year. It will contribute significantly to structural biology research in Queensland and elsewhere in Australia and also to allied fields of biotechnology, including drug discovery, bioinformatics, molecular design and functional genomics.

结构生物学正在经历一场世界性的革命，使蛋白质结构测定的速度大大加快。澳大利亚目前缺乏设施，使这种高通量的方法结构生物学。 我们计划建立一个解决这一缺陷的设施，每年将能够确定数百种新蛋白质的结构。它将为昆士兰州和澳大利亚其他地方的结构生物学研究以及生物技术的相关领域，包括药物发现、生物信息学、分子设计和功能基因组学做出重大贡献。