Identificationand the analysis of the genes involvedin photoreceptor morphogenesis and maintenance in Drosophila

我们筛选了参与视紫红质运输的新基因，并发现两个糖基磷脂酰肌醇（GPI）合成/附着过程的缺乏导致了视紫红质从TGN的顶端运输的丧失（Development, 2013）。在研究arstin介导的信号传导过程中，我们发现果蝇光受体中的Arr2易位是由扩散驱动的，但光传导和Ca2+内流深刻地加速了Arr2易位（Neuron 2010， J. Neursci. 2012）。

We screened to identify new genes involved in Rhodopsin transport andfound two that the deficiency of glycosylphosphatidylinositol (GPI) synthesis/attachment processes causes the loss of the apical transport of Rhodopsinfrom the TGN (Development, 2013). In the process of studying Arrstin mediated signaling, we found that Arr2 translocation in Drosophilaphotoreceptors is driven by diffusion, but profoundly accelerated by phototransduction and Ca2+influx (Neuron 2010, J. Neursci. 2012)