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Development of regenerative medicine of glaucoma using iPS cells

Development of regenerative medicine of glaucoma using iPS cells
利用iPS细胞开发青光眼再生医学
批准号:
21700423
负责人:
YOSHIDA Tetsu
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

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中文摘要
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英文摘要
To develop the regenerative medicine of glaucoma, I tried to introduce iPS cell into retinal ganglion cell and Muller cell, which is an adult stem cell in retina. At the same time, identivication of the marker genes of Muller cell were also taken place. First, a recombinant BAC clone, which has a red fluorescent protein DsRed gene at the position of a retinal progenitor cell marker Rx gene, was constructed. And, I found a gene called Epiplakin was a marker gene of Muller cell.
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Analysis on the expression and function of BRINP family genes during neural differentiation of mouse embryonic stem cell-derived neural stem cells
BRINP家族基因在小鼠胚胎干细胞源性神经干细胞神经分化过程中的表达及功能分析
DOI: --
发表时间: 2010
期刊: Journal of Neuroscience Research
影响因子: 4.2
作者: [Terashima M., et al.]
通讯作者: et al.
Analysis of gene expressions of ES-derived Pdx1-expressing cells : Implications of genes involved in pancreas differentiation.
ES 衍生的 Pdx1 表达细胞的基因表达分析:参与胰腺分化的基因的含义。
DOI: --
发表时间: 2009
期刊: Dev.Growth Differ. 51
影响因子: --
作者: [Yoshida T, Murata K, Shiraki N, Kume K, Kume S.]
通讯作者: Kume S.
Analysis on the expression and function of BRINP family genes during neural differentiation of mouse embryonic stem cell-derived neural stem cells.
小鼠胚胎干细胞源性神经干细胞神经分化过程中BRINP家族基因的表达及功能分析
DOI: --
发表时间: 2010
期刊: J.Neurosci.Res. 88
影响因子: --
作者: [Terashima M, Kobayashi M, Motomiya M, Inoue N, Yoshida T, Okano H, Iwasaki N, Minami A, Matsuoka I.]
通讯作者: Matsuoka I.
ヘルパー依存型アデノウイルスを用いたヒトiPS細胞の遺伝子変異治療
使用辅助依赖性腺病毒对人类 iPS 细胞进行基因突变治疗
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [吉田哲, 小泉春菜, 結城賢弥, 平林由香, 鈴木啓一郎, 三谷幸之介, 小林哲郎, 大山学, 天谷雅行, 岡田洋平, 赤松和土, 坪田一男, 榛村重人, 小沢洋子, 岡野栄之]
通讯作者: 岡野栄之
18
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