Metabolomics for elucidation of wine evaluation

阐明葡萄酒评价的代谢组学

• 批准号: 21700739
• 负责人: HISAMOTO Masashi
• 金额: $ 1.08万
• 依托单位: University of Yamanashi
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21700739/
• 关键词: ワイン; 食品; メタボロミクス

Applications of metabolomics techniques along with chemometrics provide an understanding in the relationship between metabolome of red wine and its quality. Ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry (UPLC-TOFMS) allowed a high-throughput analysis. Using this technique, a wide range of metabolites were investigated. A set of red wines during bottle storage was analyzed. Red wines with different storage time were discriminated through orthogonal partial least squares discriminate analysis (OPLS-DA). Furthermore, grape anthocyanins and pyranoanthocyanins detected in red wine were found to be significant markers to bottle aging.

代谢组学技术和化学计量学的应用为了解红酒代谢组学与品质之间的关系提供了新的思路。超高效液相色谱联用飞行时间质谱（UPLC-TOFMS）实现了高通量分析。使用这种技术，广泛的代谢物进行了研究。对一组红葡萄酒在装瓶期间的贮藏情况进行了分析。采用正交偏最小二乘鉴别分析（OPLS-DA）对不同贮藏时间的红葡萄酒进行了鉴别。此外，红葡萄酒中葡萄花青素和吡喃花青素的检测是瓶中陈酿的重要标志。

项目成果

Antioxidant Activity of Various Part of Koshu Grape

甲州葡萄各部位的抗氧化活性

• 发表时间: 2011
• 期刊: Journal of ASEV Japan Vol.22 in press
• 作者: Masashi HISAMOTO;Hirokazu MUNEDA;Tohru OKUDA
• 通讯作者: Tohru OKUDA

Differential neuroprotective activity of two different grape seed extracts.

• DOI: 10.1371/journal.pone.0014575
• 发表时间: 2011-01-24
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Narita K;Hisamoto M;Okuda T;Takeda S
• 通讯作者: Takeda S

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オンラインDPPH-HPLC法によるブドウ種子フェノール中の抗酸化化合物の探索

在线DPPH-HPLC法探索葡萄籽酚中的抗氧化成分

• 发表时间: 2011
• 期刊: 日本ブドウ・ワイン学会誌 Vol.22, No.1
• 作者: 久本 雅嗣;市川 茉利枝;依田 諭;小林浩武;奥田 徹
• 通讯作者: 奥田 徹

Phenolic off flavor characterization of commercially available wine yeasts and selection of the yeast for Koshu winemaking.

市售葡萄酒酵母的酚类异味特征以及甲州酿酒酵母的选择。

• 发表时间: 2010
• 期刊: Journal of ASEV Japan Vol.21, No.3
• 作者: Masashi Hisamoto;Taiyo Furuya;Akiko Nakagawa;Fujitoshi Yanagida;Tohru Okuda;Michikatsu Sato
• 通讯作者: Michikatsu Sato